Table I. Sulfenylated murine microsomal proteins. Proteins with respective gene names identified in microsomes of murine livers and kidneys at 5% peptide FDR. Modifications are presented as cysteine (C) and sequence location. Tissue location is denoted as liver (L) or kidney (K) by the modification.
Description | Gene Name | Modification |
---|---|---|
Carboxylesterase 3B | Ces3b | C434 (L) |
Cytochrome P450 1a2 | Cyp1a2 | C404 (L) |
Cytochrome P450 2c29 | Cyp2c29 | C435 (L)1, C216 (L), C226 (L), C372 (L) |
Cytochrome P450 2c50 | Cyp2c50 | C435 (L)1 |
Cytochrome P450 2c54 | Cyp2c54 | C435 (L)1 |
Cytochrome P450 2d10 | Cyp2d10 | C462 (L), C496 (L) |
Cytochrome P450 2d26 | Cyp2d26 | C462 (L/K)2, C496 (L) |
Cytochrome P450 2d9 | Cyp2d9 | C462 (L/K)2, C496 (L) |
Cytochrome P450 2e1 | Cyp2e1 | C488 (L/K) |
Cytochrome P450 2f2 | Cyp2f2 | C487 (L) |
Cytochrome P450 3a11 | Cyp3a11 | C64 (L), C443(L), C98(L), C239(L) |
Cytochrome P450 4a12A | Cyp4a12a | C373 (L/K) |
Cytochrome P450 4b1 | Cyp4b1 | C453 (K), C369 (K), C373 (K) |
Leukotriene-B4 ω-hydroxylase 2 | Cyp4f3 | C384 (L) |
Dimethylaniline monooxygenase, N-oxide-forming 2 | Fmo2 | C146 (K) |
Dimethylaniline monooxygenase, N-oxide-forming 5 | Fmo5 | C248 (L), C468 (L) |
Epoxide hydrolase 1 | Ephx1 | C312 (L) |
Shared peptide sequences: 1STGKRICAGEGLARMELF, 2LFFTCLLQRF.