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. 2018 Feb 5;17(5):836–849. doi: 10.1074/mcp.RA117.000560

Fig. 4.

Fig. 4.

Insulin-Signaling Cascade in HepG2 Hepatocytes. From our data set and previously characterized pathways of insulin signaling, we constructed a diagram of hepatocyte insulin signaling, including branches that control cell growth, glucose metabolism, lipid metabolism and apoptosis. Yellow: previously identified sites; Green: previously unknown sites.