Table 1.
Clinic-pathological characteristics of Triple Negative Breast Cancer subtypes.
| BLBC (n = 63) n (%) |
QNBC (n = 43) n (%) |
p-value* | |
|---|---|---|---|
| Age (years) | 58 (16) | 57 (12) | 0.78 |
| Menstrual status | 0.49 | ||
| None | 13 (45) | 7 (32) | |
| Physiological | 11 (38) | 12 (54) | |
| Post-surgery | 5 (17) | 3 (14) | |
| Site | 0.14 | ||
| Dx | 33 (59) | 17 (39) | |
| Sx | 22 (39) | 24 (56) | |
| Bilateral | 1(2) | 2 (5) | |
| Histologic subtype | 0.088 | ||
| Ductal | 42 (69) | 28 (68) | |
| Lobular | 0 (0) | 3 (7) | |
| Other subtype | 19 (31) | 10 (24) | |
| Size (cm) | 0.78 | ||
| ≤ 2 cm | 31 (51) | 22 (54) | |
| > 2 cm | 30 (49) | 19 (46) | |
| pT | 0.75 | ||
| T1-T2 | 54 (87) | 38 (91) | |
| T3-T4 | 8 (13) | 4 (9) | |
| pN | 0.407 | ||
| N0-N1 | 47 (82) | 31 (76) | |
| N2-N3 | 10 (18) | 10 (24) | |
| Grade | 0.279 | ||
| 1 | 4 (6) | 2 (5) | |
| 2 | 13 (21) | 4 (9) | |
| 3 | 46 (73) | 36 (86) | |
| Stage | 0.404 | ||
| I | 13 (23) | 13 (33) | |
| II | 30 (54) | 16 (40) | |
| III | 13 (23) | 11 (27) | |
| Necrosis | 0.188 | ||
| Present | 24 (41) | 12 (29) | |
| Absent | 34 (59) | 30 (71) | |
| Tumor infiltrating lymphocyte | 0.082 | ||
| Present | 21 (40) | 24 (58) | |
| Absent | 31 (40) | 17 (42) | |
| Lympho-vascular invasion | 0.255 | ||
| Present | 18 (35) | 10 (24) | |
| Absent | 34 (65) | 32 (76) | |
| Margin's infiltration | 0.561 | ||
| Present | 3 (8) | 1 (4) | |
| Absent | 35 (92) | 23 (96) | |
| Ki67 | 0.105 | ||
| ≤ 35% | 41 (67) | 21 (51) | |
| > 35% | 20 (33) | 20 (49) | |
| Androgen receptors | 0.854 | ||
| Present | 18 (29) | 13 (30) | |
| Absent | 45 (71) | 30 (70) | |
| Surgery | 0.507 | ||
| Mastectomy | 19 (35) | 12 (28) | |
| Lumpectomy | 1 (2) | 2 (5) | |
| Quadrantectomy | 31 (56) | 28 (65) | |
| Combined | 4 (7) | 1 (2) | |
| EGFR | < 0.0001 | ||
| Positive | 50 (79) | 0 (0) | |
| Negative | 13 (21) | 43 (100) | |
| CK 5/6 | < 0.0001 | ||
| Positive | 45 (71) | 0 (0) | |
| Negative | 18 (29) | 43 (100) |
BLBC = Basal-like breast cancer
QNBC = Quintuple negative breast cancer
n = number
*The p-values are bold where they are less than or equal to the significance level of 0.05.