Table 3.
Allelic frequency of single nucleotide polymorphisms of carbonic anhydrase 9 in patients with invasive cancer or preinvasive lesions of uterine cervix and normal women.
| Variables | Normal controls (n=324) | Preinvasive lesions (n=88) | Invasive cancer (n=97) | p value | AOR (95% CI)b | AOR (95% CI)c |
|---|---|---|---|---|---|---|
| rs2071676 | ||||||
| Gd | 326 | 90 | 87 | 0.361 | 1.00 | 1.00 |
| A | 322 | 86 | 107 | 0.88 (0.68-1.36) | 1.14 (0.79-1.65) | |
| rs3829078 | ||||||
| Ad | 617 | 167 | 186 | 0.896 | 1.00 | 1.00 |
| G | 31 | 9 | 8 | 0.90 (0.39-2.09) | 0.87 (0.35-2.14) | |
| rs1048638 | ||||||
| Cd | 611 | 164 | 172 | 0.026a | 1.00 | 1.00 |
| A | 37 | 12 | 22 | 1.29 (0.65-2.54) | 1.93 (1.02-3.64) | |
| 376deletion393 | ||||||
| Insertiond | 568 | 156 | 171 | 0.934 | 1.00 | 1.00 |
| Deletion | 80 | 20 | 23 | 0.90 (0.53-1.54) | 0.96 (0.54-1.70) |
Statistical analysis: chi-square and multiple logistic regression models for the AOR with its 95% CI after controlling for age; ap < 0.05. bComparison between patients with cervical preinvasive squamous lesions and normal women. cComparison between patients with cervical invasive saquamous cell carcinoma and normal women. dused as a reference to evaluate the odds ratio of another subtype. AOR, adjusted odds ratio; 95% CI, 95% confidence interval.