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. 2018 Mar 10;14(4):398–405. doi: 10.7150/ijbs.23268

Table 1.

Function of TNFAIP8 family member proteins.

TNFAIP8 TIPE1 TIPE2 TIPE3
Apoptosis regulation; Tumor genesis, development, metastasis, and prognosis. Pro-apoptotic protein. Negative regulator of immunity and inflammation; Maintaining homeostasis; Inhibition of tumorigenesis. Transporter of lipid second messengers;
Tumorigenesis.