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. 2018 May 2;14:146. doi: 10.1186/s12917-018-1479-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Increase of (a) serum insulin (repeated measure two-way ANOVA (rmTWA) factor oral glucose testing (OGT) p < 0.001) and of (b) glucose (rmTWA factor OGT p < 0.001) concentration in insulin-sensitive (IS) and insulin-dysregulated (ID) horses during OGT. Measurements were carried out at three levels of OGT: immediately before glucose administration (BASAL), and 120 min (OGT-120) and 180 min (OGT-180) after administration. Means ± SEM are shown, n = 10, significant differences between IS and ID are indicated as ***(p < 0.001), and a trend between IS and ID is indicated as ⁺(0.05 < p < 0.1). a, b = different superscripts indicate significant differences between basal and challenged conditions as the main OGT effect in both ID and IS horses (Bonferroni post hoc test)