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. 2018 May 2;18:57. doi: 10.1186/s12876-018-0785-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Cytokines production by peripheral blood mononuclear cells (PBMCs; 5 × 10⁵ cell) after stimulation with 5 × 10⁶ heat-killed C. albicans or C. parapsilosis isolates from HC and RTT subjects. In panels a-d) are reported the values for the cytokines produced by innate immune cells (IL-1β, IL-6, TNFα and IL-10 after 24 h of PBMCs stimulation) while in e-h) the values for the cytokines produced following adaptive immune responses (IL-17A, IL-22, IFNγ and IL-10 after 5 days of PBMCs stimulation). The dots represent each of the three replicates per isolate tested; *p < 0.05, Wilcoxon rank-sum test