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. 2018 May 1;11:34. doi: 10.1186/s13048-018-0410-3

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — The miRNA-mRNA binding sites in bovine SMAD7 3´-UTR (a, b) and ACVR2A 3´-UTR sequences (c, d), Bold and underlined letters indicate putative binding sites and mutated regions. The minimum free energies (kcal/mol) of miR-424 (e) and miR-503 (f). Schematic diagram of the reporter constructs containing the putative miRNA-mRNA binding sites of the bovine SMAD7 and ACVR2A 3´-UTR sequences (g)