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. 2018 May 2;18:499. doi: 10.1186/s12885-018-4391-9

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Effects of PCNP on the proliferation and viability of human neuroblastoma cells. a DNA replication activities of SH-SY5Y and SK-N-SH cells in each group were examined by EdU assay; original magnification 100 ×. b The proliferation rate of each group was analyzed. c The percentages of viable cells were determined using MTS assay and the cell viability of the control group was taken as 100%. d The clonogenic capacity was determined in SH-SY5Y and SK-N-SH cells. e The numbers of colonies were calculated. Data are presented as mean ± SEM of three independent experiments; *P < 0.05, **P < 0.01 compared with the Mock group; ^#P < 0.05, ^##P < 0.01 compared with the sh-Scb group