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. 2018 May 1;18:58. doi: 10.1186/s12883-018-1053-0

Table 1.

Demographic and clinical features in VPSV and VPSWOV patients

No Age/ gender Risk factors Time from diagnosis to shunt (m) neurological deficit antifungal therapy Outcome 1 m
Before VPS After VPS improved
VPSV
1 38/M Hepatitis B 4 H,VL,HL H AMBisome+Fluc+5FC better
2 36/M Hepatitis B, Liver cirrhosis 1.5 H,VL,LOC H,VL,LOC AMB + Fluc+5FC worse
3 40/M Diabetes mellitus 3 H/V H AMB + Fluc+5FC better
4 17/M 3.5 H/V,VL,LOC H/V,VL,LOC AMB + Fluc+5FC better
5 28/M 1.5 H/V,VL H,VL Fluc+5FC better
6 53/M 6 V, LOC V, LOC AMB + Fluc+5FC better
7 27/M pulmonary cryptococcosis 3 H/V,VL H/V AMB + Fluc+5FC better
8 21/M 5 H H AMB + Fluc+5FC better
9 31/M Hepatitis B, Diabetes mellitus 6 H,VL H,VL Fluc+5FC better
10 19/M AIHA 4 H/V,CO H/V,CO AMB + Fluc+5FC better
11 18/M Hepatitis B 2 H/V H/V AMB + Fluc+5FC better
12 53/F 3.5 V,LOC V,LOC AMB + Fluc+5FC better
13 50/M Hepatitis B 6 H,VL H Fluc+5FC better
VPSWOV
14 41/F pulmonary cryptococcosis 4 H/V H AMB + Fluc+5FC better
15 35/M 3 H/V,VL,LOC H/V,VL,LOC AMB + Fluc+5FC better
16 40/M pulmonary cryptococcosis 3 H/V,VL,HL H/V,VL AMB + Fluc+5FC better
17 51/M Diabetes mellitus 0.5 H/V,VL H/V,VL AMB + Fluc+5FC better
18 41/M 2 H,VL, CO H,VL AMB + Fluc+5FC better
19 61/F Malignancy 4 H/V H/V Fluc+5FC worse
20 37/M Hepatitis B 2 H/V,VL,HL H/V,VL AMB + Fluc+5FC better
21 55/F SLE 0.5 H/V,VL H/V,VL Fluc+5FC better
22 17/M pulmonary cryptococcosis 1 H/V,LOC H/V,LOC AMB + Fluc+5FC better
23 45/F AIHA 1 H,VL,HL,LOC H,VL AMB + Fluc+5FC NA

AIHA autoimmune haemolytic anaemia, SLE systemic lupus erythematosus, H/V headache and vomiting, VL visual loss, HL hearing loss, LOC loss of consciousness, CO convulsions, NA Not available, AMB Amphotericin B, 5FC flucytosine, Fluc Fluconazole, M month, 1–13: VPSV, 14–23: VPSWOV