Table 5.
Multivariate analysis with respect to DFS and OS in invasive breast cancer
| categorical | continuous | |||
|---|---|---|---|---|
| Characteristics | HR (95% CI)a | p-value a | HR (95% CI)a | p-value a |
| cNHERF1 | 0.63 (0.25, 1.60) | 0.337 | 0.99 (0.96, 1.02) | 0.416 |
| nNHERF1 | 0.60 (0.07, 5.167) | 0.640 | 0.89 (0.70, 1.12) | 0.319 |
| mNHERF1 | 3.71 (0.98, 13.99) | 0.053 | 1.09 (1.02, 1.17) | 0.011 |
| cVEGF | 0.63 (0.25, 1.61) | 0.333 | 0.99 (0.97, 1.01) | 0.249 |
| cVEGFR1 | 0.64 (0.28, 1.48) | 0.297 | 1.00 (0.98, 1.02) | 0.826 |
| MVD | 0.54 (0.23, 1.29) | 0.165 | 0.97 (0.91, 1.04) | 0.442 |
| nHIF-1α | 0.69 (0.24, 2.02) | 0.504 | 0.99 (0.95, 1.03) | 0.520 |
| nTWIST1 | 0.14 (0.05, 0.43) | 0.001 | 0.92 (0.87, 0.97) | 0.003 |
ahazard-ratio (HR) and p-value for DFS computed using the multivariate Cox proportional hazard regression model with categorical and continuous variables; HR for OS cannot be computed due to the low number of events