Table 2.
Clinical trial registration and results reporting policies
| QUESTION (number of participants who viewed the question) | No. | Percentage |
|---|---|---|
| Trial registration policies | ||
| Does the organization have a registration policy? (N = 366)a | ||
| Yes | 156 | 43% |
| No | 173 | 47% |
| Don’t know | 37 | 10% |
| Does the policy cover investigators joining the organization? (N = 156)b | ||
| Yes | 57 | 37% |
| No | 76 | 49% |
| Don’t know | 23 | 15% |
| Skipped (did not answer) | 0 | 0% |
| Does the policy cover investigators leaving the organization? (N = 156)b | ||
| Yes | 38 | 24% |
| No | 87 | 56% |
| Don’t know | 31 | 20% |
| Skipped (did not answer) | 0 | 0% |
| According to the policy, when must trials be registered? (N = 139)b,c | ||
| Before IRB approval | 15 | 11% |
| Before enrollment begins | 49 | 35% |
| Within 21 days of beginning enrollment | 31 | 22% |
| Requirements differ among trials | 21 | 15% |
| This is not addressed in the policy | 18 | 13% |
| Don’t know | 4 | 3% |
| Skipped (did not answer) | 1 | 1% |
| According to the policy, who is responsible for determining whether a trial must be registered? (N = 129)b,c | ||
| Principal investigator | 72 | 56% |
| Institutional review board | 20 | 16% |
| PRS administrator | 35 | 27% |
| Other | 14 | 11% |
| This responsibility is not assigned in the policy | 12 | 9% |
| Don’t know | 0 | 0% |
| Skipped (did not answer) | 0 | 0% |
| According to the policy, can investigators be penalized by the organization for failing to register a trial? (N = 139)b | ||
| Yes | 27 | 23% |
| No | 91 | 91% |
| Don’t know | 21 | 21% |
| Skipped (did not answer) | 0 | 0% |
| Date the trial registration policy came into effect (N = 139)b,d | ||
| Minimum (year) | 2000 | |
| Maximum (year) | 2016 | |
| Median (year) | 2013 | |
| Results reporting policies | ||
| Does the organization have a results reporting policy? (N = 366)a | ||
| Yes | 129 | 35% |
| No | 193 | 53% |
| Don’t know | 44 | 12% |
| According to the policy, who is responsible for monitoring if results are reported on time? (N = 115)b,c | ||
| Principal investigator | 54 | 47% |
| Institutional review board | 5 | 4% |
| PRS administrator | 68 | 59% |
| Other | 12 | 10% |
| This responsibility is not assigned in the policy | 18 | 16% |
| Don’t know | 1 | 1% |
| Skipped (did not answer) | 0 | 0% |
| According to the policy, can investigators be penalized by the organization for failing to report a trial (N = 114)e | ||
| Yes | 21 | 18% |
| No | 75 | 66% |
| Don’t know | 18 | 16% |
| Skipped (did not answer) | 0 | 0% |
aAn answer to this question was required for an account to be included in the analysis; accounts that did not see or skipped this question were excluded from all analyses
bThe number of possible responses (i.e., the denominator) includes the accounts with a relevant policy that viewed this question. The number of accounts that viewed each question is less than the total number of accounts in the study because (1) participants did not see all questions because of skip logic, and (2) some participants discontinued the survey before viewing all questions
cBecause participants could “check all that apply,” the sum of all categories exceeds the number of participants who responded (i.e., some participants selected multiple responses)
dBecause 50 (36%) selected “Don’t know,” 89 accounts are included in the analysis
eOf 111 accounts who viewed either question about penalties for (1) failing to register or (2) failing to report a trial, 17 (15%) responded “Yes” to both questions, and 31 (28%) responded “Yes” to one or both questions