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. 2018 May 1;16:114. doi: 10.1186/s12967-018-1489-4

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Postprandial serum CA125 fluctuations mimicked in animal models. a Shown are the time-dependent serum CA125 fluctuations after administration of saline, glucose, insulin or glucose plus insulin in SKOV-3, HO8910, ES-2 and OVCAR-3 xenograft nude mouse models. b Comparison of the percentages of serum CA125 increase after administration of glucose or glucose plus insulin among nude mouse models and diabetes nude mouse models. The oral glucose-induced increments in serum CA125 were significantly lower in the diabetes animal models than in the non-diabetes animal models. *Statistical significance (ANOVA)