Table 3.
Verbal memory | Working memory | Motor speed | Verbal fluency | Attention | Executive function | Composite | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
β | p | β | p | β | p | β | p | β | p | β | p | β | p | |
<Male patients> | R2 = 0.09 | R2 = 0.08 | R2 = 0.16 | R2 = 0.18 | R2 = 0.29 | R2 = 0.003 | R2 = 0.27 | |||||||
Handgrip strength (kg) | 0.15 | 0.21 | 0.16 | 0.19 | 0.29 | 0.01 | 0.23 | 0.05 | 0.47 | 4.0E-05 | 0.10 | 0.44 | 0.36 | 1.4E-03 |
Age (years) | −0.13 | 0.29 | −0.10 | 0.41 | 0.10 | 0.41 | 0.11 | 0.35 | −0.14 | 0.21 | 0.08 | 0.51 | −0.02 | 0.86 |
Education (years) | 0.15 | 0.22 | 0.15 | 0.23 | −0.04 | 0.72 | −0.05 | 0.68 | 0.08 | 0.48 | 0.02 | 0.87 | 0.08 | 0.47 |
Body mass idex (kg/m2) | −0.22 | 0.09 | −0.23 | 0.07 | −0.40 | 1.3.E-03 | −0.29 | 0.02 | −0.26 | 0.02 | −0.11 | 0.39 | −0.36 | 2.2E-03 |
CPeq total antipsychotics (mg/day) | −0.11 | 0.36 | −0.05 | 0.67 | −0.19 | 0.12 | 0.01 | 0.91 | −0.07 | 0.50 | 0.10 | 0.42 | −0.07 | 0.50 |
Any psychotropic medication use (%) | −0.09 | 0.48 | −0.11 | 0.40 | 0.09 | 0.47 | −0.34 | 5.9.E-03 | −0.14 | 0.20 | −0.26 | 0.05 | −0.21 | 0.06 |
<Female patients> | R2 = 0.25 | R2 = 0.22 | R2 = 0.35 | R2 = 0.13 | R2 = 0.30 | R2 = 0.16 | R2 = 0.37 | |||||||
Handgrip strength (kg) | 0.16 | 0.16 | 0.10 | 0.36 | 0.34 | 1.5E-03 | 0.25 | 0.04 | 0.36 | 1.4E-03 | 0.16 | 0.18 | 0.30 | 5.1.E-03 |
Age (years) | −0.35 | 2.5.E-03 | −0.19 | 0.10 | 0.05 | 0.61 | −0.06 | 0.60 | −0.14 | 0.19 | −0.19 | 0.11 | −0.20 | 0.05 |
Education (years) | 0.26 | 0.03 | 0.17 | 0.16 | 0.21 | 0.05 | 0.25 | 0.04 | 0.14 | 0.21 | 0.00 | 0.98 | 0.22 | 0.04 |
Body mass idex (kg/m2) | −0.16 | 0.17 | −0.34 | 6.9.E-03 | −0.15 | 0.18 | −0.25 | 0.05 | −0.29 | 0.01 | −0.05 | 0.69 | −0.26 | 0.02 |
CPeq total antipsychotics (mg/day) | −0.09 | 0.45 | −0.17 | 0.18 | −0.17 | 0.14 | 0.02 | 0.89 | −0.22 | 0.07 | −0.37 | 6.9.E-03 | −0.23 | 0.05 |
Any psychotropic medication use (%) | −0.11 | 0.38 | −0.05 | 0.73 | −0.32 | 0.01 | −0.06 | 0.68 | −0.06 | 0.65 | −0.03 | 0.82 | −0.14 | 0.25 |
<Male controls> | R2 = 0.24 | R2 = 0.24 | R2 = 0.13 | R2 = 0.08 | R2 = 0.32 | R2 = 0.04 | R2 = 0.28 | |||||||
Handgrip strength (kg) | 0.01 | 0.89 | 0.01 | 0.89 | 0.03 | 0.70 | −0.01 | 0.89 | −0.01 | 0.93 | 0.12 | 0.14 | 0.04 | 0.63 |
Age (years) | −0.46 | 3.9.E-08 | −0.46 | 3.9.E-08 | −0.23 | 0.01 | −0.06 | 0.48 | −0.49 | 1.0.E-09 | −0.16 | 0.08 | −0.36 | 6.4.E-06 |
Education (years) | −0.11 | 0.16 | 0.03 | 0.72 | 0.19 | 0.01 | 0.24 | 3.5.E-03 | 0.16 | 0.02 | 0.13 | 0.11 | 0.27 | 2.9E-04 |
Body mass idex (kg/m2) | 0.03 | 0.72 | −0.11 | 0.16 | −0.16 | 0.07 | −0.08 | 0.37 | −0.09 | 0.23 | −0.03 | 0.71 | −0.15 | 0.06 |
<Female controls> | R2 = 0.10 | R2 = 0.08 | R2 = 0.00 | R2 = 0.08 | R2 = 0.17 | R2 = 0.05 | R2 = 0.19 | |||||||
Handgrip strength (kg) | 0.04 | 0.60 | 0.04 | 0.58 | 0.07 | 0.39 | 0.14 | 0.06 | 0.15 | 0.04 | 0.06 | 0.46 | 0.14 | 0.06 |
Age (years) | −0.23 | 4.8.E-03 | −0.10 | 0.23 | 0.00 | 0.97 | 0.10 | 0.25 | −0.20 | 0.01 | −0.02 | 0.77 | −0.12 | 0.11 |
Education (years) | 0.17 | 0.04 | 0.14 | 0.08 | 0.01 | 0.88 | 0.27 | 9.3.E-04 | 0.24 | 2.2.E-03 | 0.23 | 5.4.E-03 | 0.29 | 1.5E-04 |
Body mass idex (kg/m2) | −0.06 | 0.44 | −0.21 | 5.8.E-03 | −0.15 | 0.06 | −0.12 | 0.11 | −0.17 | 0.02 | −0.07 | 0.38 | −0.22 | 2.8.E-03 |
CPeq, chlorpromazine-equivalent dose. Significant p-values (p < 0.0071; corrected for multiple testing) are shown in bold exponents.