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. 2018 Apr 25;9:156. doi: 10.3389/fpsyt.2018.00156

Table 3.

Multiple regression analysis for each sex involving Brief Assessment of Cognition in Schizophrenia (BACS) scores and forced-entry variables.

Verbal memory Working memory Motor speed Verbal fluency Attention Executive function Composite
β p β p β p β p β p β p β p
<Male patients> R2 = 0.09 R2 = 0.08 R2 = 0.16 R2 = 0.18 R2 = 0.29 R2 = 0.003 R2 = 0.27
Handgrip strength (kg) 0.15 0.21 0.16 0.19 0.29 0.01 0.23 0.05 0.47 4.0E-05 0.10 0.44 0.36 1.4E-03
Age (years) −0.13 0.29 −0.10 0.41 0.10 0.41 0.11 0.35 −0.14 0.21 0.08 0.51 −0.02 0.86
Education (years) 0.15 0.22 0.15 0.23 −0.04 0.72 −0.05 0.68 0.08 0.48 0.02 0.87 0.08 0.47
Body mass idex (kg/m2) −0.22 0.09 −0.23 0.07 −0.40 1.3.E-03 −0.29 0.02 −0.26 0.02 −0.11 0.39 −0.36 2.2E-03
CPeq total antipsychotics (mg/day) −0.11 0.36 −0.05 0.67 −0.19 0.12 0.01 0.91 −0.07 0.50 0.10 0.42 −0.07 0.50
Any psychotropic medication use (%) −0.09 0.48 −0.11 0.40 0.09 0.47 −0.34 5.9.E-03 −0.14 0.20 −0.26 0.05 −0.21 0.06
<Female patients> R2 = 0.25 R2 = 0.22 R2 = 0.35 R2 = 0.13 R2 = 0.30 R2 = 0.16 R2 = 0.37
Handgrip strength (kg) 0.16 0.16 0.10 0.36 0.34 1.5E-03 0.25 0.04 0.36 1.4E-03 0.16 0.18 0.30 5.1.E-03
Age (years) −0.35 2.5.E-03 −0.19 0.10 0.05 0.61 −0.06 0.60 −0.14 0.19 −0.19 0.11 −0.20 0.05
Education (years) 0.26 0.03 0.17 0.16 0.21 0.05 0.25 0.04 0.14 0.21 0.00 0.98 0.22 0.04
Body mass idex (kg/m2) −0.16 0.17 −0.34 6.9.E-03 −0.15 0.18 −0.25 0.05 −0.29 0.01 −0.05 0.69 −0.26 0.02
CPeq total antipsychotics (mg/day) −0.09 0.45 −0.17 0.18 −0.17 0.14 0.02 0.89 −0.22 0.07 −0.37 6.9.E-03 −0.23 0.05
Any psychotropic medication use (%) −0.11 0.38 −0.05 0.73 −0.32 0.01 −0.06 0.68 −0.06 0.65 −0.03 0.82 −0.14 0.25
<Male controls> R2 = 0.24 R2 = 0.24 R2 = 0.13 R2 = 0.08 R2 = 0.32 R2 = 0.04 R2 = 0.28
Handgrip strength (kg) 0.01 0.89 0.01 0.89 0.03 0.70 −0.01 0.89 −0.01 0.93 0.12 0.14 0.04 0.63
Age (years) −0.46 3.9.E-08 −0.46 3.9.E-08 −0.23 0.01 −0.06 0.48 −0.49 1.0.E-09 −0.16 0.08 −0.36 6.4.E-06
Education (years) −0.11 0.16 0.03 0.72 0.19 0.01 0.24 3.5.E-03 0.16 0.02 0.13 0.11 0.27 2.9E-04
Body mass idex (kg/m2) 0.03 0.72 −0.11 0.16 −0.16 0.07 −0.08 0.37 −0.09 0.23 −0.03 0.71 −0.15 0.06
<Female controls> R2 = 0.10 R2 = 0.08 R2 = 0.00 R2 = 0.08 R2 = 0.17 R2 = 0.05 R2 = 0.19
Handgrip strength (kg) 0.04 0.60 0.04 0.58 0.07 0.39 0.14 0.06 0.15 0.04 0.06 0.46 0.14 0.06
Age (years) −0.23 4.8.E-03 −0.10 0.23 0.00 0.97 0.10 0.25 −0.20 0.01 −0.02 0.77 −0.12 0.11
Education (years) 0.17 0.04 0.14 0.08 0.01 0.88 0.27 9.3.E-04 0.24 2.2.E-03 0.23 5.4.E-03 0.29 1.5E-04
Body mass idex (kg/m2) −0.06 0.44 −0.21 5.8.E-03 −0.15 0.06 −0.12 0.11 −0.17 0.02 −0.07 0.38 −0.22 2.8.E-03

CPeq, chlorpromazine-equivalent dose. Significant p-values (p < 0.0071; corrected for multiple testing) are shown in bold exponents.