Table 4.
Verbal memory | Working memory | Motor speed | Verbal fluency | Attention | Executive function | Composite | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
β | p | β | p | β | p | β | p | β | p | β | p | β | p | |
<Patients with schizophrenia> | R2 = 0.19 | R2 = 0.19 | R2 = 0.23 | R2 = 0.15 | R2 = 0.32 | R2 = 0.09 | R2 = 0.35 | |||||||
Handgrip strength/body mass index (m2) | 0.26 | 0.01 | 0.35 | 9.7.E-04 | 0.47 | 1.2E-05 | 0.40 | 2.3.E-04 | 0.56 | 2.9E-08 | 0.15 | 0.17 | 0.51 | 1.8E-07 |
Age (years) | −0.26 | 1.7.E-03 | −0.14 | 0.08 | 0.06 | 0.47 | 0.01 | 0.91 | −0.14 | 0.06 | −0.07 | 0.39 | −0.13 | 0.08 |
Sex | 0.19 | 0.07 | 0.06 | 0.53 | 0.38 | 2.0.E-04 | 0.21 | 0.05 | 0.37 | 9.4E-05 | −0.11 | 0.29 | 0.26 | 4.6.E-03 |
Education (years) | 0.22 | 0.01 | 0.17 | 0.04 | 0.07 | 0.36 | 0.10 | 0.21 | 0.12 | 0.12 | 0.04 | 0.65 | 0.17 | 0.02 |
CPeq total antipsychotics (mg/day) | −0.10 | 0.24 | −0.08 | 0.33 | −0.17 | 0.04 | 0.01 | 0.91 | −0.13 | 0.10 | −0.10 | 0.27 | −0.13 | 0.09 |
Any psychotropic medication use (%) | −0.10 | 0.25 | −0.10 | 0.25 | −0.09 | 0.30 | −0.18 | 0.04 | −0.07 | 0.37 | −0.15 | 0.10 | −0.16 | 0.04 |
<Healthy controls> | R2 = 0.19 | R2 = 0.09 | R2 = 0.02 | R2 = 0.08 | R2 = 0.25 | R2 = 0.06 | R2 = 0.22 | |||||||
Handgrip strength / body mass index (m2) | 0.10 | 0.15 | 0.14 | 0.04 | 0.10 | 0.19 | 0.13 | 0.08 | 0.17 | 0.01 | 0.12 | 0.10 | 0.20 | 2.6.E-03 |
Age (years) | −0.37 | 5.7.E-12 | −0.20 | 3.7.E-04 | 0.00 | 0.98 | 0.00 | 0.93 | −0.37 | 9.9.E-13 | −0.09 | 0.12 | −0.28 | 1.3.E-07 |
Sex | 0.25 | 2.3.E-04 | 0.07 | 0.35 | 0.10 | 0.19 | 0.24 | 1.1.E-03 | 0.27 | 4.5.E-05 | 0.02 | 0.78 | 0.25 | 1.7.E-04 |
Education (years) | 0.08 | 0.12 | 0.16 | 4.8.E-03 | 0.15 | 0.01 | 0.25 | 1.2.E-05 | 0.18 | 3.1.E-04 | 0.18 | 1.6.E-03 | 0.27 | 3.7.E-07 |
CPeq, chlorpromazine-equivalent dose. Significant p-values (p < 0.0071; corrected for multiple testing) are shown in bold exponents. Sex was coded as male: 1 and female: 2.