Table 5.
Multivariable linear regression analysis of predictors of HRQoL of HIV-infected patients with and without VL in northwest Ethiopia, 2016
| Patient characteristics | HRQoL domains | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Physical domain (β-coefficient) | Psychological domain (β-coefficient) | Social domain (β-coefficient) | Spiritual domain (β-coefficient) | Level of independence (β-coefficient) | Environmental domain (β-coefficient) | |||||||
| HIV–VL (N = 75) | HIV (N = 439) | HIV–VL (N = 75) | HIV (N = 439) | HIV–VL (N = 75) | HIV (N = 439) | HIV–VL (N = 75) | HIV (N = 439) | HIV–VL (N = 75) | HIV (N = 439) | HIV–VL (N = 75) | HIV (N = 439) | |
| Gender | – | – | – | – | – | – | – | – | – | – | – | – |
| Male | −0.59 | |||||||||||
| Female | Ref. | |||||||||||
| Income source | – | – | ||||||||||
| Yes | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | ||
| No | −1.14 | −0.35 | −1.35* | −1.15** | −0.76** | −0.96 | −1.87** | −1.07** | −2.05** | −2.28** | ||
| Social support | ||||||||||||
| Yes | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
| No | −0.30 | −0.77** | −1.41* | −2.89** | −4.11** | −4.39** | −1.21 | −0.32 | −0.47 | −1.55** | −1.54** | −2.19** |
| Adherence of ART | – | – | – | – | – | – | – | – | – | – | ||
| Yes | Ref. | Ref. | ||||||||||
| No | −0.18 | −0.09 | ||||||||||
| Adherence of anti-VL | – | – | – | – | – | – | – | – | – | |||
| Yes | Ref. | Ref. | Ref. | |||||||||
| No | −1.73 | −2.57 | −1.11 | |||||||||
| Nutritional status | ||||||||||||
| SAM | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. | Ref. |
| MAM | 2.33** | 1.28** | 1.21 | 1.45* | 1.47* | 1.27* | 0.86 | 1.15* | 1.93** | 1.17* | 1.22 | 0.94 |
| Normal | 2.53 | 1.48** | 1.99 | 1.42* | 1.03 | 1.08* | 1.66 | 0.81 | 3.06* | 1.38* | −0.15 | 0.85 |
| Obese | – | 2.02* | – | 0.39 | – | 0.21 | – | 2.74* | – | 1.17 | – | 0.25 |
| P value of multivariate regression model | P = 0.001 | P = 0.001 | P = 0.002 | P = 0.001 | P = 0.001 | P = 0.001 | P = 0.055 | P = 0.069 | P = 0.001 | P = 0.001 | P = 0.001 | P = 0.001 |
| Adjusted R2 | 0.197 | 0.085 | 0.172 | 0.219 | 0.546 | 0.449 | 0.080 | 0.011 | 0.256 | 0.125 | 0.263 | 0.318 |
ART = antiretroviral therapy; HIV = human immunodeficiency virus; HRQoL = health related quality of life; MAM = moderate acute malnutrition; Ref. = reference category; SAM = severe acute malnutrition; VL = visceral leishmaniasis. *P = value < 0.05; **P = value < 0.01.