Table 3.

Distribution of glutamate-rich protein R2 alleles in Plasmodium falciparum field isolates as observed in 2004 and 2015

Types	Allele variants (50 bp bin)	2004 (N = 110) n (%)	2015 (N = 89) n (%)	P value
I	500–550	2 (2)	0 (0)	NS
II	550–600	0 (0)	0 (0)	NS
III	600–650	4 (4)	0 (0)	NS
IV	650–700	1 (1)	0 (0)	NS
V	700–750	11 (10)	3 (3)	NS
VI	750–800	5 (5)	0 (0)	NS
VII	800–850	11 (10)	7 (8)	NS
VIII	850–900	9 (8)	16 (18)	NS
IX	900–950	12 (11)	9 (10)	NS
X	950–1,000	4 (4)	1 (1)	NS
XI	1,000–1,050	26 (24)	9 (10)	0.014*
XII	1,050–1,100	1 (1)	2 (2)	NS
I + III	500–550 + 600–650	2 (2)	5 (6)	NS
I + IV	500–550 + 650–700	0 (0)	1 (1)	NS
I + VII	500–550 + 800–850	0 (0)	1 (1)	NS
I + VIII	500–550 + 850–900	0 (0)	1 (1)	NS
II + IV	550–600 + 650–700	1 (1)	0 (0)	NS
II + V	550–600 + 700–750	2 (2)	0 (0)	NS
III + V	600–650 + 700–750	5 (5)	7 (8)	NS
III + VI	600–650 + 750–800	0 (0)	2 (2)	NS
IV + VII	650–700 + 800–850	1 (1)	0 (0)	NS
V + VII	700–750 + 800–850	2 (2)	4 (5)	NS
V + VIII	700–750 + 850–900	2 (2)	4 (5)	NS
V + XI	700–750 + 1,000–1,050	0 (0)	1 (1)	NS
VI + VII	750–800 + 800–850	1 (1)	0 (0)	NS
VI + VIII	750–800 + 850–900	0 (0)	3 (3)	NS
VI + IX	750–800 + 900–950	0 (0)	1 (1)	NS
VII + VIII	800–850 + 850–900	0 (0)	3 (3)	NS
VII + XI	800–850 + 1,000–1,050	2 (2)	2 (2)	NS
VIII + IX	850–900 + 900–950	0 (0)	3 (3)	NS
IX + X	900–950 + 950–1,000	1 (1)	2 (2)	NS
IX + XI	900–950 + 1,000–1,050	3 (3)	2 (2)	NS
X + XII	950–1,000 + 1,050–1,100	1 (1)	0 (0)	NS
V + VII + IX	700–750 + 800–850 + 900–950	1 (11)	0 (0)	NS

^*Significant P < 0.005; NS = not significant.