Table 3.

Subgroup meta-analysis^* of studies reporting JEV dissemination rates in vectors grouped by mosquito species

Mosquito species†	N‡	Effect size (logit)	95% CI (logit)	JEV dissemination rates§	95% CI (rates)	% Weight	I-squared (%)‖
Culex annulirostris	5	−0.40	−1.48, 0.68	0.40	0.19, 0.66	21.90	85.4
Culex gelidus	1	−1.21	−1.68, −0.74	0.23	0.16, 0.32	5.26	–
Culex pipiens	1	−0.41	−2.19, 1.37	0.40	0.10, 0.80	3.20	–
Culex quinquefasciatus	5	0.42	−0.57, 1.41	0.60	0.36, 0.80	22.26	82.6
Culex sitiens	4	−1.44	−2.28, −0.60	0.19	0.09, 0.35	16.41	51.7
Ochlerotatus detritus	3	1.18	−0.11, 2.46	0.76	0.47, 0.92	12.21	69.7
Ochlerotatus notoscriptus	1	−2.44	−3.48, −1.40	0.08	0.03, 0.20	4.44	–
Ochlerotatus vigilax	2	−1.09	−2.12, −0.06	0.25	0.11, 0.49	9.35	62.1
Opifex fuscus	1	0.85	0.14, 1.56	0.70	0.54, 0.83	4.96	–
Overall	–	−0.33	−0.83, 0.16	0.42	0.30, 0.54	100.00	–

CI = confidence interval; JEV = Japanese encephalitis virus. Each effect size¶ represents pooled estimates of the outcome for each mosquito species and the overall represents the overall pooled estimate across all mosquito species. N = 23 entries.

^*Random-effects meta-analysis using the method of DerSimonian and Laird²⁵ to estimate the variance between studies, using a restricted maximum likelihood algorithm.

^†Species are reported as recorded in the original articles.

^‡Entries correspond to the times a certain mosquito species was recorded within a specific outcome (≠ number of articles, i.e., several entries may pertain to the same article).

^§$p=\left({\mathrm{e}}^{\mathrm{logit}}/\left[{\text{e}}^{\text{logit}}+1\right]\right).$

^‖I-squared = proportion of total variability in point estimates that can be attributed to heterogeneity. I² range: 62.1% (Ochlerotatus vigilax, P-value = 0.04) to 85.4% (Culex annulirostris, P value = 0.47).

^¶Computed for the group of studies reporting JEV dissemination rates in each mosquito species.