Table 1.
Demographic information of study populations used for determination of diagnostic performance
| Characteristic | Group | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Onchocerca volvulus–infected | Non-helminth–infected | Helminth-infected | |||||||||
| O. volvulus Cameroon | O. volvulus Ghana | HC southern Africa | HC Belgium | HIV | HCV | Dengue | Asthma | Wb | Bm | STH | |
| Origin | Cameroon | Ghana | Southern Africa | Belgium | USA | USA | Vietnam | USA | Sri Lanka (8) | Indonesia (Central Sulawesi) | Indonesia (Flores) |
| Tahiti (2) | |||||||||||
| Number of patients | 13 | 97 | 10 | 49 | 25 | 25 | 25 | 25 | 10 | 20 | 20 |
| Age, median (min–max) | 54 (20–72) | 47 (21–85) | 21 (17–47) | 40 (23–59) | n.a. | n.a. | 26 (4–67) | 46 (17–91) | 33 (13–48) | 19 (10–45) | 40 (25–75) |
| Gender, n (%) | |||||||||||
| Male | 6 (46) | 54 (56) | 7 (70) | 22 (45) | n.a. | n.a. | 10 (40) | 11 (44) | 6 (60) | 10 (50) | 2 (10) |
| Female | 7 (54) | 43 (44) | 3 (30) | 27 (55) | n.a. | n.a. | 15 (60) | 14 (56) | 3 (30) | 10 (50) | 18 (90) |
| Unknown | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 1 (10) | 0 (0) | 0 (0) |
| Source* | FR3 | KCCR | TS | Janssen | MC | MC | DLS | BR | FR3 | UI | UI |
| Ov16 IgG4 positive, n | 12 | 66 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Bm = Brugia malayi; HC = healthy control; HCV = hepatitis C virus; HIV = human immunodeficiency virus; IgG4 = immunoglobulin G4; n.a. = not available; STH = soil-transmitted helminths; Wb = Wuchereria bancrofti.
*
BR = Bioreclamation; DLS = Discovery Life Sciences; FR3 = Filariasis Research Reagent Resource Center; KCCR = Kumasi Center for Collaborative Research; MC = Mayo Clinic; TS = Tissue Solutions; UI = Universitas Indonesia.