Table 3.
Four genomic segments harboring a SOX10 consensus sequence display regulatory activity in Schwann cells
| Region | Fold-increase Forward |
Fold-increase Reverse |
Coordinates (hg18)a | rs Number | MAFb |
|---|---|---|---|---|---|
| rSOX-1 | 2.57 | 8.29 | chr2:44834620-44834625 | rs3738980 | 0.3035 |
| rSOX-4 | 4.83 | 25.96 | chr6:22818474-22818479 | rs16886790 | 0.2001 |
| rSOX-6 | 0.33 | 11.01 | chr6:98692222-98692227 | rs17814604 | 0.1014 |
| rSOX-22 | 14.12 | 4.44 | chr16:53169712-53169728 | rs1186802 | 0.4219 |
aCoordinates for the conserved SOX10 monomeric sites for rSOX-1, −4, and − 6 and the dimeric site for rSOX-22
bMAF is the minor allele frequency from the 1000 Genomes Project [72]