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. 2018 May 2;18:495. doi: 10.1186/s12885-018-4410-x

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Immunohistochemistry staining of triple negative breast cancer and lung adenocarcinoma tissues with E-Ig chimera and HECA-452 monoclonal antibody. E-Ig was used for staining the E-selectin ligands in triple negative breast cancer (a and c) and in lung adenocarcinoma (e and g) tissues. sLe^X and sLe^A were stained with HECA-452 antibody in triple negative breast cancer (b and d) and in lung adenocarcinoma (f and h) tissues. Brown color indicates E-Ig or HECA-452 positive reactivity. Images were taken in sequences from the same tissue section of the same paraffin block of tumor tissue, with a 10× magnification