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. 2018 Apr 19;3(8):e99922. doi: 10.1172/jci.insight.99922

Figure 1. EoE WES study design.

Figure 1

Schematic depicting the workflow for whole-exome sequencing (WES) filtering of rare, damaging variants, de novo variants, and compound heterozygous variants in 63 patients with eosinophilic esophagitis (EoE) and 60 unaffected family members. Filtering details can be found in Methods. Alt, alternate; GQ, genotype quality score; DP, read depth; MAF, minor allele frequency; KBAC, kernel-based adaptive cluster. Asterisk indicates one of the families (trio) included an unaffected sibling and a grandparent.