Fig. 6. Real-time monitoring of the operation of the nanomachine in HeLa cells. HeLa cells were incubated with the 0.2 nM nanomachine (S2/R1/A6-AuNP) for 20 min, 40 min, 60 min, 80 min and 120 min, respectively, and collected to image immediately using a Nikon confocal scanning system. 0 min represents that the HeLa cells were not incubated with the nanomachine.