Table 3.
Trait | Standardized canonical coefficient |
IL1A | IL1B | IL6 | TNFA |
ADAMTS 4 |
ADAMTS 5 |
BMP2 | MMP1 | MMP3 | MMP9 | MMP13 | IL8 | CCL3 | CCL3L1 | CXCL1 | CXCL3 | CXCL6 | CCL20 | COL1A1 | COL2A1 | ACAN | NFKB1A | NFKB2 | IKBA | ADIPOQ | APLN | LEP | RETN |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IL1A | 1.91 | 1 | |||||||||||||||||||||||||||
IL1B | 1.23 | 0.73 | 1 | ||||||||||||||||||||||||||
IL6 | 0.33 | 0.77 | 0.77 | 1 | |||||||||||||||||||||||||
TNFA | −1.01 | 0.84 | 0.77 | 0.72 | 1 | ||||||||||||||||||||||||
ADAMTS4 | 0.37 | 0.51 | 0.47 | 0.54 | 0.49 | 1 | |||||||||||||||||||||||
ADAMTS5 | −1.16 | 0.4 | 0.31 | 0.37 | 0.28 | 0.75 | 1 | ||||||||||||||||||||||
BMP2 | −0.07 | 0.57 | 0.63 | 0.72 | 0.55 | 0.59 | 0.53 | 1 | |||||||||||||||||||||
MMP1 | −0.07 | 0.35 | 0.46 | 0.29 | 0.43 | 0.39 | 0.18 | 0.16 | 1 | ||||||||||||||||||||
MMP3 | −0.8 | 0.31 | 0.38 | 0.38 | 0.21 | 0.37 | 0.44 | 0.43 | 0.31 | 1 | |||||||||||||||||||
MMP9 | −0.55 | 0.58 | 0.67 | 0.67 | 0.62 | 0.54 | 0.45 | 0.54 | 0.27 | 0.19 | 1 | ||||||||||||||||||
MMP13 | 1.43 | 0.43 | 0.51 | 0.56 | 0.48 | 0.63 | 0.64 | 0.52 | 0.4 | 0.43 | 0.53 | 1 | |||||||||||||||||
IL8 | −0.4 | 0.36 | 0.51 | 0.51 | 0.41 | 0.43 | 0.17 | 0.3 | 0.55 | 0.3 | 0.35 | 0.39 | 1 | ||||||||||||||||
CCL3 | −0.82 | 0.77 | 0.79 | 0.72 | 0.75 | 0.47 | 0.32 | 0.57 | 0.34 | 0.21 | 0.56 | 0.53 | 0.37 | 1 | |||||||||||||||
CCL3L1 | −0.32 | 0.69 | 0.81 | 0.72 | 0.72 | 0.46 | 0.25 | 0.65 | 0.39 | 0.29 | 0.65 | 0.51 | 0.47 | 0.78 | 1 | ||||||||||||||
CXCL1 | −0.38 | 0.64 | 0.77 | 0.77 | 0.69 | 0.57 | 0.38 | 0.56 | 0.33 | 0.26 | 0.63 | 0.62 | 0.51 | 0.68 | 0.67 | 1 | |||||||||||||
CXCL3 | −0.55 | 0.79 | 0.78 | 0.71 | 0.77 | 0.43 | 0.24 | 0.52 | 0.36 | 0.32 | 0.62 | 0.43 | 0.26 | 0.83 | 0.78 | 0.67 | 1 | ||||||||||||
CXCL6 | 0.23 | 0.67 | 0.71 | 0.76 | 0.65 | 0.46 | 0.2 | 0.56 | 0.34 | 0.4 | 0.51 | 0.39 | 0.46 | 0.7 | 0.75 | 0.69 | 0.76 | 1 | |||||||||||
CCL20 | −0.56 | 0.71 | 0.71 | 0.62 | 0.71 | 0.33 | 0.13 | 0.42 | 0.48 | 0.33 | 0.5 | 0.38 | 0.43 | 0.66 | 0.71 | 0.57 | 0.76 | 0.73 | 1 | ||||||||||
COL1A1 | 0.06 | 0.16 | 0.33 | 0.25 | 0.23 | 0.32 | 0.3 | 0.1 | 0.41 | 0.29 | 0.22 | 0.53 | 0.56 | 0.1 | 0.18 | 0.32 | 0.08 | 0.08 | 0.3 | 1 | |||||||||
COL2A1 | −0.58 | 0.29 | 0.39 | 0.24 | 0.34 | 0.07 | −0.2 | 0.02 | 0.41 | 0.03 | 0.12 | 0.16 | 0.42 | 0.11 | 0.31 | 0.38 | 0.3 | 0.23 | 0.41 | 0.5 | 1 | ||||||||
ACAN | −0.25 | 0.41 | 0.44 | 0.36 | 0.42 | −0.03 | −0.2 | 0.22 | 0.18 | −0.05 | 0.27 | −0.24 | 0.02 | 0.31 | 0.38 | 0.28 | 0.47 | 0.48 | 0.44 | −0.26 | 0.24 | 1 | |||||||
NFKB1A | 0.2 | 0.3 | 0.49 | 0.39 | 0.38 | 0.49 | 0.21 | 0.28 | 0.5 | 0.34 | 0.39 | 0.44 | 0.68 | 0.22 | 0.44 | 0.42 | 0.24 | 0.32 | 0.4 | 0.64 | 0.53 | 0.1 | 1 | ||||||
NFKB2 | −0.4 | 0.53 | 0.62 | 0.55 | 0.48 | 0.51 | 0.35 | 0.38 | 0.53 | 0.51 | 0.49 | 0.4 | 0.62 | 0.41 | 0.56 | 0.56 | 0.49 | 0.57 | 0.57 | 0.37 | 0.39 | 0.37 | 0.69 | 1 | |||||
IKBA | 0.47 | 0.35 | 0.57 | 0.29 | 0.45 | 0.27 | 0.13 | 0.23 | 0.57 | 0.32 | 0.32 | 0.26 | 0.62 | 0.21 | 0.46 | 0.37 | 0.31 | 0.31 | 0.45 | 0.62 | 0.63 | 0.21 | 0.77 | 0.69 | 1 | ||||
ADIPOQ | 0.72 | 0.35 | 0.4 | 0.25 | 0.38 | 0.18 | 0.12 | 0.23 | 0.33 | 0.23 | 0.38 | 0.08 | 0.26 | 0.23 | 0.44 | 0.33 | 0.47 | 0.38 | 0.41 | −0.02 | 0.19 | 0.46 | 0.23 | 0.42 | 0.35 | 1 | |||
APLN | 0.88 | 0.39 | 0.38 | 0.35 | 0.36 | 0.26 | 0.24 | 0.27 | 0.18 | 0.28 | 0.35 | 0.07 | 0.25 | 0.42 | 0.35 | 0.33 | 0.45 | 0.5 | 0.5 | −0.14 | −0.06 | 0.51 | 0.08 | 0.56 | 0.09 | 0.48 | 1 | ||
LEP | −0.56 | 0.54 | 0.55 | 0.48 | 0.59 | 0.49 | 0.29 | 0.37 | 0.24 | 0.08 | 0.46 | 0.32 | 0.31 | 0.57 | 0.63 | 0.48 | 0.58 | 0.59 | 0.45 | 0.09 | 0.12 | 0.39 | 0.21 | 0.34 | 0.24 | 0.6 | 0.44 | 1 | |
RETN | 0.2 | 0.41 | 0.49 | 0.39 | 0.47 | 0.15 | 0.05 | 0.22 | 0.1 | 0.02 | 0.46 | 0.13 | 0.08 | 0.34 | 0.44 | 0.45 | 0.55 | 0.38 | 0.44 | 0.09 | 0.19 | 0.46 | 0.07 | 0.36 | 0.27 | 0.52 | 0.35 | 0.46 | 1 |