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. Author manuscript; available in PMC: 2018 May 2.
Published in final edited form as: Diabetes Metab Res Rev. 2012 Sep;28(6):519–526. doi: 10.1002/dmrr.2305

Table 4. Risk reclassification of 283 Insulin Resistance Atherosclerosis Study participants with impaired fasting glucose and/or the metabolic syndrome by Diabetes Risk Score (DRS) compared with classification by number of metabolic syndrome risk factors present.

Risk group by number of metabolic syndrome risk factors present Risk group by DRS No. reclassified [%]

Low (<4.5) Moderate (4.5–7.9) High (≥8.0) Any DRS
1–2 risk factors
 Number of observations 12 39 31 82 70
 Fraction of population 4.2% 13.8% 11.0% 29.0% 85.4%
 Number converted at 5 years 1 6 15 22
 Fraction converted at 5 years 8.3% 15.4% 48.4% 26.8%
3 risk factors
 Number of observations 27 59 48 134 75
 Fraction of population 9.5% 20.8% 17.0% 47.3% 56.0%
 Number converted at 5 years 2 13 19 34
 Fraction converted at 5 years 7.4% 22.0% 39.6% 25.4%
4–5 risk factors
 Number of observations 5 17 45 67 22
 Fraction of population 1.8% 6.0% 15.9% 23.7% 32.8%
 Number converted at 5 years 0 3 26 29
 Fraction converted at 5 years 0% 19.1% 57.8% 43.3%
Any number of risk factors
 Number of observations 44 115 124 283 167
 Fraction of population 15.5% 40.6% 43.8% 100% 59.0%
 Number converted at 5 years 3 22 60 85
 Fraction converted at 5 years 6.8% 19.1% 48.4% 30.0%

A significant net reclassification improvement of 0.24 was observed (p =0.01).