Table 4. Risk reclassification of 283 Insulin Resistance Atherosclerosis Study participants with impaired fasting glucose and/or the metabolic syndrome by Diabetes Risk Score (DRS) compared with classification by number of metabolic syndrome risk factors present.
Risk group by number of metabolic syndrome risk factors present | Risk group by DRS | No. reclassified [%] | |||
---|---|---|---|---|---|
| |||||
Low (<4.5) | Moderate (4.5–7.9) | High (≥8.0) | Any DRS | ||
1–2 risk factors | |||||
Number of observations | 12 | 39 | 31 | 82 | 70 |
Fraction of population | 4.2% | 13.8% | 11.0% | 29.0% | 85.4% |
Number converted at 5 years | 1 | 6 | 15 | 22 | |
Fraction converted at 5 years | 8.3% | 15.4% | 48.4% | 26.8% | |
3 risk factors | |||||
Number of observations | 27 | 59 | 48 | 134 | 75 |
Fraction of population | 9.5% | 20.8% | 17.0% | 47.3% | 56.0% |
Number converted at 5 years | 2 | 13 | 19 | 34 | |
Fraction converted at 5 years | 7.4% | 22.0% | 39.6% | 25.4% | |
4–5 risk factors | |||||
Number of observations | 5 | 17 | 45 | 67 | 22 |
Fraction of population | 1.8% | 6.0% | 15.9% | 23.7% | 32.8% |
Number converted at 5 years | 0 | 3 | 26 | 29 | |
Fraction converted at 5 years | 0% | 19.1% | 57.8% | 43.3% | |
Any number of risk factors | |||||
Number of observations | 44 | 115 | 124 | 283 | 167 |
Fraction of population | 15.5% | 40.6% | 43.8% | 100% | 59.0% |
Number converted at 5 years | 3 | 22 | 60 | 85 | |
Fraction converted at 5 years | 6.8% | 19.1% | 48.4% | 30.0% |
A significant net reclassification improvement of 0.24 was observed (p =0.01).