Table 2.
Main and Interaction Effects of Cortisol and Testosterone on Hippocampal Volume and Episodic Memory
| Estimate | SE | F | DF | p | |
|---|---|---|---|---|---|
| Hippocampal Volume | |||||
| Testosterone | 0.0076 | 0.0452 | 0.03 | 1;150 | .8662 |
| Cortisol | −0.0140 | 0.0427 | 0.11 | 1;150 | .7428 |
| Interaction | 0.1088 | 0.0378 | 8.29 | 1;150 | .0046 |
| Episodic Memory | |||||
| Testosterone | 0.0649 | 0.0372 | 3.05 | 1;311 | .0820 |
| Cortisol | −0.0441 | 0.0397 | 1.44 | 1;311 | .2308 |
| Interaction | 0.0833 | 0.0309 | 7.28 | 1;311 | .0074 |
All analyses control for age, ethnicity, history of hypertension, history of cardiovascular disease, history of diabetes, current smoking status, current alcohol use, and self-report depressive symptoms. The analysis of hippocampal volume also control for scanner, and estimated ICV. The analysis of episodic memory includes age 20 general cognitive ability as an additional covariate. Significant effects are presented in bold font. F and p values represent the type III test of fixed effects.