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. 2018 May 2;9(5):501. doi: 10.1038/s41419-018-0504-2

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a G3BP1 expression in 16 pairs of primary RCC (T) and adjacent normal kidney tissues (N) were examined by Western blot. Upper panel: representative four pairs of Western blot images. Lower panel: the expression of G3BP1 was quantified by normalizing with β-actin, and all 16 pairs of RCC patient samples were analyzed using a paired t-test, p = 0.012. b G3BP1 expression was examined by immunohistochemistry staining in a study cohort with 43 pairs of RCC (tumor) and adjacent normal kidney tissues (para-tumor). Representative G3BP1 staining of RCC and paired non-tumor sections were shown, and brown signal indicated the G3BP1-positive staining.