Table 1.

Correlation between G3BP1 expression and clinicopathologic characteristics in RCC patients

			G3BP1 expression
		N	−	+	p Value
Gender	Male	29	12	17	0.159
	Female	14	9	5
Age	<60	16	8	8	0.907
	≥60	27	13	14
Tumor size	<4	6	4	2	0.188
	>4, ≤7	6	1	5
	>7	31	16	15
TNM stage	T1–2	25	20	5	0.000*
	T3–4	18	1	17
Fuhrman grade	I, II	27	17	10	0.027*
	III, IV	16	4	12
Location	Tumor	43	21	22	0.015*
	Para-tumor	43	32	11
RCC subtype	ccRCC	38	19	19	1.000
	Non-ccRCC	5	2	3
Tumor side	Left	19	12	7	0.095
	Right	24	9	15
Necrosis	Negative	15	5	10	0.137
	Positive	28	16	12

Note: G3BP1 expression (−/+) was determined by IHC staining score. The scoring system was composed of two independent parameters: percentage of tumor cells exhibiting positive staining (0–5: 0–1%; 1–5%; 6–10%; 11–20%; 21–50%; >50%); and intensity of IHC staining (0–2: 0, no staining; yellow-brown staining; strong brown staining). The final scores of two parameters were added to a sum and defined as the IHC staining score. 0–3: Negative; 4–7: Positive.

*p  < 0.05 indicates statistical significance by χ² test.