Table 2. Echocardiographic variables stratified by new ASE/EACVI Recommendations.
| All (N = 237) | Grade I (N = 41) | Grade II (N = 111) | Grade III (N = 80) | Cannot determine (N = 5) | P value | |
|---|---|---|---|---|---|---|
| MR > 2+ | 30 (13%) | 0 | 7 (6%) | 23 (29%) | 0 | < 0.001 |
| Severe MAC | 70 (30%) | 7 (17%) | 43 (39%) | 18 (23%) | 2 (40%) | 0.021 |
| MS > mild (n = 237) | 7 (3%) | 2 (5%) | 5 (5%) | 0 | 0 | 0.26 |
| LVEF > 50% (n = 237) | 134 (57%) | 29 (71%) | 73 (66%) | 27 (34%) | 5 (100%) | < 0.001 |
| LVEF (%) (n = 237) | 49±14 | 53±13 | 53±12 | 42±15 | 62±3 | < 0.001 |
| E/e’ (n = 220) | 23±13 | 14.0±4.6 | 24.1±13.7 | 27.1±13.4 | 15.3±1.7 | < 0.001 |
| E’ septal (m/sec) (n = 221) | 0.05±0.02 | 0.06±0.02 | 0.05±0.02 | 0.05±0.02 | 0.04±0.01 | 0.008 |
| E’ lateral (m/sec)(n = 220) | 0.06±0.02 | 0.07±0.02 | 0.06±0.02 | 0.06±0.02 | 0.07±0.01 | 0.267 |
| LAVi (ml/m2) (n = 237) | 56±29 | 35.8±15.9 | 57.3±26.1 | 66.1±33.1 | 45.1±20.5 | < 0.001 |
| TR velocity (m/sec) (n = 217) | 2.29±1.46 | 2.42±0.77 | 2.99±0.64 | 3.28±0.65 | NA | < 0.001 |
| E/A (n = 182) | 1.40±0.95 | 0.91±0.38 | 1.11±0.40 | 3.06±1.03 | 0.75±0.15 | < 0.001 |
| E (m/sec) (n = 235) | 1.16±0.38 | 0.88±0.31 | 1.18±0.40 | 1.30±0.30 | 0.85±0.10 | < 0.001 |
| DT (msec) (n = 233) | 215±84 | 241±105 | 233±84 | 173±46 | 246±123 | < 0.001 |
| S/D (n = 178) | 0.96±0.59 | 1.29±0.60 | 1.05±0.50 | 0.65±0.57 | NA | < 0.001 |
| S/D < 1.0 (n = 178) | 106 (56%) | 11 (37%) | 46 (51%) | 49 (86%) | 0 | < 0.001 |
Abbreviations: MR, mitral regurgitation; MAC, mitral annular calcification; MS, mitral stenosis; LVEF, left ventricular ejection fraction; LAVi, left atrial volume index; TR, tricuspid regurgitation; DT, deceleration time.