Table 2. Percentage of relapsing mice and bacterial burden in mice vaccinated SC with increasing vaccination number of MVATG18598 during antibiotic regimen.
Treatment | No. of inject. | Relapses | Bacterial load at relapse CFU (log10) (mean ± SEM) |
|
---|---|---|---|---|
Proportion | % | |||
RHZ | - | 10 / 12 | 83 | 2.3 ± 0.5 |
RHZ + MVATG18598 | 3x | 6 / 12 | 50 | 1.2 ± 0.5 |
RHZ + MVATG18598 | 5x | 8 / 12 | 67 | 2.2 ± 0.5 |
RHZ + MVATG18598 | 7x | 7 / 12 | 58 | 1.9 ± 0.5 |
R, Rifampin; H, Isoniazid; Z, Pyrazinamide.