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. 2018 May 2;4(5):eaao1478. doi: 10.1126/sciadv.aao1478

Fig. 3. Variants have distinct transcriptional signatures.

Fig. 3

Pools of LCVs and SCVs were assayed in duplicate. (A) Hierarchical clustering analysis of genes differentially expressed more than threefold. (B) Volcano plot analysis of RNA-seq data comparing gene expression profiles of SCVs and LCVs. Dots indicated in red and blue are genes that are down-regulated and up-regulated, respectively, in the SCVs more than twofold with a P value of <0.01. (C) Gene categories of genes differentially expressed >10-fold in LCVs versus SCVs.

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