Table 3. Number and frequency of DNA mutations that occur in tandem within framework regions (FR) and complementarity determining regions (CDR) in nurse shark alpha V (αV) groups.
All mutations include both tandem and point mutations within a region. [Seqs: sequences]
| FR | CDR | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| # Nucleotides Tandemly Mutated | All mutation | Frequency of tandem mutation | # Nucleotides Tandemly Mutated | All mutation | Frequency of tandem mutation | ||||||||
| αV Group | # Seqs | 2 | 3 | 4 | Sum | 2 | 3 | 4 | Sum | ||||
| αV1.1 | 3 | 1 | 0 | 1 | 6 | 24 | 25.0 | 3 | 0 | 0 | 6 | 12 | 50.0 |
| αV1.2 | 5 | 4 | 1 | 0 | 11 | 37 | 29.7 | 5 | 1 | 0 | 13 | 17 | 76.5 |
| αV1.4 | 3 | 3 | 0 | 0 | 6 | 14 | 42.9 | 0 | 0 | 0 | 0 | 3 | 0.0 |
| αV2 | 5 | 0 | 0 | 0 | 0 | 1 | 0.0 | 0 | 0 | 0 | 0 | 1 | 0.0 |
| αV3 | 4 | 2 | 0 | 0 | 4 | 5 | 80.0 | 1 | 0 | 0 | 2 | 3 | 66.7 |
| αV4.1 | 2 | 4 | 1 | 0 | 11 | 23 | 47.8 | 0 | 1 | 0 | 3 | 7 | 42.9 |
| αV4.2 | 2 | 1 | 1 | 0 | 5 | 11 | 45.5 | 0 | 1 | 0 | 3 | 2 | 150.0 |
| αV5 | 2 | 1 | 0 | 0 | 2 | 14 | 14.3 | 1 | 1 | 0 | 5 | 10 | 50.0 |
| αV7.2 | 2 | 4 | 1 | 0 | 11 | 22 | 50.0 | 1 | 0 | 0 | 2 | 4 | 50.0 |
| αV10.1 | 4 | 3 | 0 | 0 | 6 | 6 | 100.0 | 0 | 0 | 0 | 0 | 6 | 0.0 |
| αV10.2 | 9 | 4 | 1 | 0 | 11 | 35 | 31.4 | 2 | 1 | 0 | 7 | 16 | 43.8 |
| Total | 41 | 27 | 5 | 1 | 73 | 192 | 38.0 | 13 | 5 | 0 | 41 | 81 | 50.6 |