Table 1.
Differentially expressed Synechococcus host genes between high and low light conditions during infection with cyanophage S-PM2. Positive and negative log2 fold changes indicate up/down regulation respectively with respect to the low light treatment
| Locus Tag | Gene Name | Annotation | Functional group | Log2 Fold Change in expression | adj-p-value |
|---|---|---|---|---|---|
| Upregulated | |||||
| SYNWH7803_0424 | rplN | 50 S ribosomal protein L14 | Translation | 1.348 | 3.41E−02 |
| SYNWH7803_2372 | rplJ | 50 S ribosomal protein L10 | Translation | 1.246 | 2.41E−12 |
| SYNWH7803_0434 | rplC | 50 S ribosomal protein L3 | Translation | 1.240 | 1.69E−08 |
| SYNWH7803_0431 | rplB | 50 S ribosomal protein L2 | Translation | 1.209 | 4.96E−05 |
| SYNWH7803_1329 | rpsB | 30 S ribosomal protein S2 | Translation | 1.200 | 9.88E−06 |
| SYNWH7803_0429 | rplV | 50 S ribosomal protein L22 | Translation | 1.171 | 1.23E−02 |
| SYNWH7803_0422 | rplE | 50 S ribosomal protein L5 | Translation | 1.138 | 8.77E−05 |
| SYNWH7803_0427 | rplP | 50 S ribosomal protein L16 | Translation | 1.102 | 1.23E−02 |
| SYNWH7803_2374 | rplK | 50 S ribosomal protein L11 | Translation | 1.089 | 3.85E−04 |
| SYNWH7803_0591 | rpsD | 30 S ribosomal protein S4 | Translation | 1.072 | 3.53E−03 |
| SYNWH7803_0433 | rplD | 50 S ribosomal protein L4 | Translation | 1.033 | 5.82E−03 |
| SYNWH7803_0428 | rpsC | 30 S ribosomal protein S3 | Translation | 1.033 | 2.68E−03 |
| SYNWH7803_0418 | rpsE | 30 S ribosomal protein S5 | Translation | 1.003 | 5.55E−03 |
| SYNWH7803_0423 | rplX | 50 S ribosomal protein L24 | Translation | 1.001 | 1.76E−03 |
| SYNWH7803_0420 | rplF | 50 S ribosomal protein L6 | Translation | 0.972 | 1.66E−03 |
| SYNWH7803_2371 | rplL | 50 S ribosomal protein L7/L12 | Translation | 0.924 | 8.30E−06 |
| SYNWH7803_2373 | rplA | 50 S ribosomal protein L1 | Translation | 0.805 | 1.56E−02 |
| SYNWH7803_1863 | groEL | 60 kDa chaperonin 2 | Posttranslational modification, protein turnover, chaperones | 1.520 | 7.06E−15 |
| SYNWH7803_1118 | ahpC | Peroxiredoxin, AhpC/TSA family | Posttranslational modification, protein turnover, chaperones | 1.315 | 3.65E−05 |
| SYNWH7803_1998 | groEL | 60 kDa chaperonin 1 | Posttranslational modification, protein turnover, chaperones | 1.171 | 5.63E−12 |
| SYNWH7803_0023 | SynWH7803_0023 | DnaJ-class molecular chaperone | Posttranslational modification, protein turnover, chaperones | 1.043 | 3.61E−02 |
| SYNWH7803_2514 | dnaK | Molecular chaperone DnaK | Posttranslational modification, protein turnover, chaperones | 0.849 | 5.15E−07 |
| SYNWH7803_0016 | msrB | Peptide methionine sulfoxide reductase | Posttranslational modification, protein turnover, chaperones | 0.758 | 1.18E−03 |
| SYNWH7803_1999 | groES | 10 kDa chaperonin | Posttranslational modification, protein turnover, chaperones | 0.743 | 1.82E−02 |
| SYNWH7803_1555 | pepN | Aminopeptidase N | Posttranslational modification, protein turnover, chaperones | 0.603 | 2.50E−02 |
| SYNWH7803_0790 | psbA | Photosystem II protein D1 | Photosynthesis | 1.795 | 8.48E−04 |
| SYNWH7803_2084 | psbA | Photosystem II protein D1 | Photosynthesis | 1.695 | 5.50E−04 |
| SYNWH7803_0366 | psbA | Photosystem II protein D1 | Photosynthesis | 1.578 | 5.53E−04 |
| SYNWH7803_1861 | fabG | 3-oxoacyl-[acyl-carrier-protein] reductase | Fatty acid biosynthesis | 1.023 | 4.52E−02 |
| SYNWH7803_1870 | SynWH7803_1870 | Uncharacterised protein required for cytochrome oxidase assembly | Energy production and conversion | 1.599 | 3.16E−03 |
| SYNWH7803_2017 | atpA | ATP synthase alpha chain | Energy production and conversion | 0.718 | 1.21E−02 |
| SYNWH7803_2495 | cynS | Cyanate lyase | Cyanate metabolism | 0.616 | 3.14E−03 |
| SYNWH7803_0169 | ahcY | Adenosylhomocysteinase | Coenzyme transport and metabolism | 1.219 | 1.18E−03 |
| SYNWH7803_2069 | SynWH7803_2069 | Carbohydrate-binding protein; modular; contains a central CBM2 module | Carbohydrate transport and metabolism | 1.998 | 4.00E−11 |
| SYNWH7803_1930 | glgX | Glycogen debranching enzyme | Carbohydrate transport and metabolism | 1.814 | 1.08E−03 |
| SYNWH7803_1423 | SynWH7803_1423 | Conserved hypothetical protein | 1.490 | 4.99E−02 | |
| SYNWH7803_2070 | SynWH7803_2070 | Two-component system response regulator | 1.119 | 5.22E−03 | |
| SYNWH7803_0046 | SynWH7803_0046 | DHSS soluble hydrogenase, small subunit | 0.809 | 4.27E−02 | |
| SYNWH7803_1728 | SynWH7803_1728 | Integral membrane protein | 0.586 | 1.82E−02 | |
| Downregulated | |||||
| SYNWH7803_0611 | rpoD | RNA polymerase sigma factor RpoD, sigma-70 family | Transcription | −0.746 | 1.22E−04 |
| SYNWH7803_2501 | rpoD | Alternative RNA polymerase sigma factor, sigma-70 family | Transcription | −1.037 | 4.76E−04 |
| SYNWH7803_1592 | trxA | Thioredoxin | Redox homoeostasis | −0.882 | 7.75E−04 |
| SYNWH7803_2137 | SynWH7803_2137 | Predicted ATPase with chaperone activity | Posttranslational modification, protein turnover, chaperones | −1.957 | 9.76E−03 |
| SYNWH7803_0353 | psbO | Photosystem II manganese-stabilising protein PsbO | Photosynthesis | −0.500 | 4.78E−02 |
| SYNWH7803_0984 | petJ | Cytochrome C6 | Photosynthesis | −0.739 | 4.36E−02 |
| SYNWH7803_0252 | ndhC | NAD(P)H-quinone oxidoreductase chain 3 | Photosynthesis | −0.768 | 3.63E−02 |
| SYNWH7803_0391 | psaA | Photosystem I P700 chlorophyll A apoprotein A1 | Photosynthesis | −0.829 | 1.46E−06 |
| SYNWH7803_0534 | petD | Cytochrome b6-f complex subunit 4 | Photosynthesis | −0.869 | 1.18E−03 |
| SYNWH7803_1224 | psaK | Photosystem I reaction centre subunit X, PsaK | Photosynthesis | −0.983 | 1.45E−03 |
| SYNWH7803_0396 | psaL | Photosystem I reaction centre subunit XI | Photosynthesis | −1.001 | 3.18E−04 |
| SYNWH7803_0392 | psaB | Photosystem I P700 chlorophyll A apoprotein A2 | Photosynthesis | −1.078 | 2.41E−12 |
| SYNWH7803_0502 | mpeD | Phycobilisome linker polypeptide, C-phycoerythrin-associated | Light Harvesting | −0.543 | 2.88E−02 |
| SYNWH7803_0500 | SynWH7803_0500 | Conserved hypothetical protein in phycobilisome rod gene region | Light Harvesting | −0.884 | 6.12E−04 |
| SYNWH7803_0493 | mpeB | C-phycoerythrin class II beta chain | Light Harvesting | −1.034 | 7.27E−10 |
| SYNWH7803_0501 | cpeE | Phycobilisome linker polypeptide, C-phycoerythrin class I-associated | Light Harvesting | −1.042 | 4.63E−05 |
| SYNWH7803_0492 | mpeA | C-phycoerythrin class II alpha chain | Light Harvesting | −1.312 | 1.05E−09 |
| SYNWH7803_0670 | chlL | Protoporphyrin IX Mg-chelatase subunit ChlD | Chlorophyll biosynthesis | −1.493 | 5.53E−15 |
| SYNWH7803_0029 | gap1 | Glyceraldehyde-3-phosphate dehydrogenase | Central carbon metabolism | −0.944 | 5.50E−04 |
| SYNWH7803_0543 | SynWH7803_0543 | LysM-repeat protein | Cell wall/membrane biogenesis | −0.533 | 9.89E−03 |
| SYNWH7803_1746 | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | Cell wall/membrane biogenesis | −1.010 | 1.37E−02 |
| SYNWH7803_1841 | pilT | Twitching motility protein | Cell motility | −1.435 | 3.85E−14 |
| SYNWH7803_1798 | SynWH7803_1798 | Uncharacterized conserved secreted protein, pili subunit superfamily | Cell motility | −1.524 | 4.63E−08 |
| SYNWH7803_1796 | SynWH7803_1796 | Uncharacterized conserved secreted protein, pili subunit superfamily | Cell motility | −1.540 | 1.21E−12 |
| SYNWH7803_1795 | SynWH7803_1795 | Uncharacterized conserved secreted protein, pili subunit superfamily | Cell motility | −1.658 | 9.13E−29 |
| SYNWH7803_0756 | SynWH7803_0756 | Alpha-glycosidase of family GH13; possible 1, 4-alpha-glucan branching enzyme | Carbohydrate transport and metabolism | −1.070 | 3.15E−03 |
| SYNWH7803_1937 | SynWH7803_1937 | Conserved hypothetical protein | −0.547 | 1.83E−02 | |
| SYNWH7803_0291 | SynWH7803_0291 | Conserved hypothetical protein | −0.657 | 5.56E−03 | |
| SYNWH7803_1897 | SynWH7803_1897 | Uncharacterized conserved secreted protein | −0.659 | 4.11E−02 | |
| SYNWH7803_0551 | SynWH7803_0551 | Hypothetical protein | −0.659 | 1.18E−02 | |
| SYNWH7803_2356 | SynWH7803_2356 | Uncharacterized conserved secreted protein | −0.750 | 1.18E−03 | |
| SYNWH7803_0849 | SynWH7803_0849 | Conserved hypothetical protein | −0.864 | 1.59E−02 | |
| SYNWH7803_0308 | SynWH7803_0308 | Secreted protein with pentapeptide repeats | −0.912 | 2.42E−03 | |
| SYNWH7803_2182 | SynWH7803_2182 | Conserved hypothetical protein | −0.922 | 1.77E−05 | |
| SYNWH7803_0069 | SynWH7803_0069 | Conserved hypothetical protein | −1.122 | 7.64E−04 | |
| SYNWH7803_2423 | SynWH7803_2423 | Conserved hypothetical protein | −1.160 | 2.20E−04 | |
| SYNWH7803_1348 | SynWH7803_1348 | Hypothetical protein | −1.325 | 9.08E−04 | |
| SYNWH7803_0705 | SynWH7803_0705 | Hypothetical protein | −1.393 | 3.38E−06 | |
| SYNWH7803_0839 | SynWH7803_0839 | Hypothetical protein | −1.394 | 1.56E−02 | |
| SYNWH7803_1797 | SynWH7803_1797 | Uncharacterized conserved secreted protein | −1.509 | 2.30E−03 | |
| SYNWH7803_2085 | SynWH7803_2085 | Uncharacterized conserved secreted protein | −1.612 | 2.27E−08 | |
| SYNWH7803_1502 | SynWH7803_1502 | Conserved hypothetical membrane protein | −1.629 | 9.89E−03 | |
| SYNWH7803_1800 | SynWH7803_1800 | Uncharacterized conserved membrane protein | −1.655 | 4.20E−17 | |
| SYNWH7803_0463 | SynWH7803_0463 | Uncharacterized conserved membrane protein | −1.757 | 3.86E−04 | |
| SYNWH7803_0464 | pex | Possible Pex protein (Period-extender gene product) | −2.178 | 9.21E−12 | |
| SYNWH7803_0940 | SynWH7803_0940 | Conserved hypothetical protein | −2.185 | 3.01E−14 | |
| SYNWH7803_2186 | SynWH7803_2186 | Conserved hypothetical protein | −2.274 | 7.21E−20 | |
| SYNWH7803_0934 | SynWH7803_0934 | Hypothetical protein | −3.056 | 2.56E−88 | |