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. 2018 May 2;8:6934. doi: 10.1038/s41598-018-25121-4

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Synteny analyses of T1R3 genes. The adjacent genes of T1R3 were partially conserved. The solute carrier family 45 member 1 (SLC45A1), prothymosin alpha-like (ProT α), coiled-coil domain containing 114 (CCDC114) genes located upstream of T1R3 in most fishes. The ERBB receptor feedback inhibitor 1 (ERRFI1) was always next to the T1R3 gene in fish. Mitochondrial ribosomal protein S16 (MRPS16) and paired box 7a (PAX7a) genes are frequently downstream of fish T1R3.