Fig. 4.

CML progression affected by DDX43 overexpression. DDX43-K562 or control cells were injected via tail vein into SCID mice. a The ratio of decreased weight of SCID mice injected with K562 transfected cells. Data shown were mean ± SD from three experiments. b The ratio of increased WBC of SCID mice injected with K562 transfected cells. c Mice were killed after 4 weeks of injection and blasts in bone marrow of SCID mice injected with DDX43-K562 transfected cells were detected with Wright−Giemsa stain. d Mice were photographed and killed after 4 weeks of injection. *P < 0.05. Error bars indicate SD (n = 5)