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. 2018 May 2;8:6932. doi: 10.1038/s41598-018-24351-w

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Histopathology of myocardium from Lamp2^y/− rats and wild-type rats (8 weeks). (a) Gross morphology of the heart; (b) Masson Trichrome staining; (c) Immunohistochemical reactivity for MAb B7, a marker for myocardium microvascular endothelial cells³²; (d) Periodic Acid Schiff (PAS) staining. Bars in (a) correspond to 2 mm. The black bars correspond to 200 μm, and the yellow bars correspond to 2 mm in (b,c and d). WT, wild-type male rats; KO, Lamp2^y/− rats.