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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Mol Cancer Ther. 2018 Feb 26;17(5):1070–1078. doi: 10.1158/1535-7163.MCT-17-1053

Figure 4.

Figure 4

Influence of GSKJ4 on the repair of radiation-induced DNA damage. A) Neutral comet assay. U251 and MDA-MB-231 cells were treated with vehicle (DMSO) or GSKJ4 (4μM) immediately before irradiation (10Gy) and analyzed at times out to 24h. Data are expressed as percent damage remaining with the Olive tail moment immediately after radiation corresponding to 100% damage. Values shown represent the mean ± SEM for 3 to 4 independent experiments. B) γH2AX expression. U251 or MDA-MB-231 cells were treated with vehicle (DMSO) or GSKJ4 (4μM) immediately before irradiation (6Gy) and collected for analysis 16h later. Values shown represent the mean ± SEM for 3 independent experiments. *p≤0.04 according to Student’s t test.