. Author manuscript; available in PMC: 2019 May 1.

Published in final edited form as: Clin Cancer Res. 2018 Feb 20;24(9):2225–2233. doi: 10.1158/1078-0432.CCR-17-1904

Table 4.

Correlation of serum TGF-β1 expression levels with tumor HPV16 status and TGF-β1 genotypes in 162 SCCOP patients

Variables	No. patients	Serum TGF-β1 level (Mean ± SD, pg/ml)	p (by unpaired t test)
All patients (N = 162)

Tumor HPV16 status			0.045
Negative	42	10.2 ± 8.1
Positive	120	14.2 ± 11.9

TGF-β1 rs1800469			0.161
CC^b	107	12.5 ± 10.2
CT + TT	55	10.2 ± 9.1
TGF-β1 rs1982073			0.021
TT^b	48	9.9 ± 8.2
CT + CC	114	13.9 ± 10.6
TGF-β1 rs1800471			0.276
GG^b	124	13.1 ± 11.3
CG + CC	38	10.9 ± 9.2

HPV16 positive patients (N = 120)

TGF-β1 rs1800469			0.657
CC^b	79	14.7 ± 10.3
CT + TT	41	13.8 ± 10.9
TGF-β1 rs1982073			0.048
TT^b	39	12.0 ± 8.4
CT + CC	81	16.3 ± 12.1
TGF-β1 rs1800471			0.544
GG^b	93	15.2 ± 11.1
CG + CC	27	13.7 ± 11.9