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. 2018 Apr 26;9:428. doi: 10.3389/fphar.2018.00428

Table 1.

Monomers and active components of medicinal plants in ischemic heart disease.

Classification Name Source Models Targets Reference
Replenishing and activating blood Salvianolic acid A Radix Salvia miltiorrhiza In vivo JNK/PI3K/Akt↓; EPCs, MSCs↑ Guo et al., 2014; Li et al., 2014; Chen et al., 2016
Tanshinone IIA Radix Salvia miltiorrhiza In vivo VEGF and HIF-1a↑ Xu et al., 2009
Ferulaic acid Radix Angelica Sinensis In vivo VEGF, AKT/mTOR↑ Liu et al., 2009; Zhang Q. et al., 2017
Invigorating and replenishing Qi Rhodiola Rhizoma Rhodiolae Kirilowii In vivo Flt-1, Tie-2, HIF-1a, HIF-1β↑ Li et al., 2005; Gao et al., 2009
Salidroside Rhizoma Rhodiolae Kirilowii In vivo Unknown Zhang J. et al., 2017
Astragalosides Shanxi Astragalus membranaceus In vivo VEGF and bFGF↑ Yu et al., 2015
Other active components of medicinal plants Berberine Berberis and Berberis aristata In vivo/in vitro miR-29b↑ Zhu et al., 2017
Puerarin Radix Puerariae In vivo VEGF and eNOS↑ Zhang S. et al., 2006
Extract of Geum japonicum Germ japonicum In vivo Unknown Li et al., 2006