Table 6.
Comparisons between the groups with high and low expression of hypoxia inducible factor (HIF)-1α in relation to sleep-disordered breathing variables and intermittent/continuous hypoxia indicators.
| Variable | HIF-1α high expression (n = 16) | HIF-1α non-high expression (n = 360) | p-Value |
|---|---|---|---|
| Apnea–hypopnea index (/h) | 24.1 (17.8) | 14.5 (16.3) | 0.37 |
| DI4% (/h) | 18.8 (16.6) | 9.8 (13.5) | 0.081 |
| Mean SpO2 | 93.5 (1.41) | 93.8 (1.9) | 0.153 |
| Nadir SpO2 | 79.1 (12.8) | 83.7 (9.1) | 0.008 |
| Tsat <90% | 5.2 (6.8) | 5.85 (12.7) | 0.329 |
| Epworth score | 6.6 (3.3) | 6.1 (3.6) | 0.88 |
Bold fond indicates p < 0.05.