Table 4.
Various biosensors designed for microbial detection.
Microbial sensor | Biomarker measuring mechanism | Analytical measurement | Limit of detection |
---|---|---|---|
Pseudomonas aeruginosa | Pyocyanin metabolite from wound exudatea | Electrochemical | 56 CFU/mL |
ecfX, ExoS, and ExoU genesb | mLAMP, LFNAB, colorimetric | 20 CFU/mL | |
Phage binding to hostc | Electrochemiluminescent | 56 CFU/mL | |
Staphylococcus aureus | anti-S. aureus aptamerd | Potentiometric transducer | Covalent 8 × 102 CFU/mL Non-covalent 107 CFU/mL |
Proteolytic activitye | Colorimetric | 7 CFU/mL |