Table 1.
Demographic and baseline characteristics of 26 patients with HCC
| Variable | N=26 |
|---|---|
|
| |
| Median age - year | 65 (range 44–74) |
|
| |
| Sex – no. (%) | |
| Men | 20 (76.9%) |
|
| |
| * BCLC stage – no. (%) | |
| B | 3 (11.5%) |
| C | 12 (46.2%) |
| D | 3 (11.5%) |
|
| |
| * Child-Pugh class – no. (%) | |
| A | 4 (15.4%) |
| B | 13 (50.0%) |
| C | 7 (26.9%) |
| N/A | 2 (7.7%) |
|
| |
| ECOG performance status – no. (%) | |
| 0 | 2 (7.7%) |
| 1 | 8 (30.8%) |
| 2 | 11 (42.3%) |
| 3 | 5 (19.2%) |
|
| |
| Risk Factors: All patients – no. (%) | |
| Hepatitis B | 1 (3.8%) |
| Hepatitis C | 17 (65.4%) |
| Alcohol | 3 (11.5%) |
| Metabolic Syndrome | 5 (19.2%) |
|
| |
| Number of patients with tissue next generation sequencing | 10 (38.4%) |
|
| |
| Risk Factors: Ten patients with both liquid and tissue biopsy – no. (%) | N=10 |
| Hepatitis B | 0 (0.0%) |
| Hepatitis C | 8 (80.0%) |
| Alcohol | 1 (10.0%) |
| Metabolic Syndrome | 1 (10.0%) |
|
| |
| Number of patients with ≥ 1 characterized alteration (%) | 23 (88.5%) |
Abbreviations: BCLC = Barcelona Clinic Liver Cancer Staging; ECOG = Eastern Cooperative Oncology Group; HCC = hepatocellular carcinoma
*
Data not available for all patients