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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Mol Cancer Ther. 2018 Feb 26;17(5):1079–1089. doi: 10.1158/1535-7163.MCT-17-0137

Figure 2. Other nonseminomatous GCT histologies also exhibit highly active mTORC1 signaling.

Figure 2

A, IHC staining for phosphorylated S6 in embryonal carcinoma (top) and choriocarcinoma (bottom). B, phospho-S6 IHC intensity score in GCT histologies. Horizontal bar represents mean values for each histology. YST: yolk sac tumor; CC: Choriocarcinoma; EC: Embryonal Carcinoma; SEM: Seminoma. p-values for comparison with SEM: YST <0.001; CC 0.0002; EC <0.0001 (2–tailed Student’s t-test). C, IHC for phosphorylated S6 in NCCIT and NTERA-2 cells.