Table 1.
Distribution of predicted c-di-GMP metabolic proteins in Leptospira species.
| Strains | Pathogenicity | GGDEF only | PAS-GGDEF | REC-GGDEF | GAF-GGDEF | Cache1-GGDEF | 7TMR-DISM-GGDEF | PilZ-GGDEF | Total number of GGDEF | EAL only | REC-EAL | YkuI_C-EAL | Total number of EAL | GGDEF-EAL only | PAS-GGDEF-EAL | REC-GGDEF-EAL | Total number of GGDEF-EAL | HD-GYP only | GAF-HD-GYP | REC-HDGYP | Total number of HD-GYP | Total number | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| L. borgpetersenii | Hardjo-bovis str.L550 | pathogenic | 2 | 1 | 1 | 2 | 1 | 7 | 3 | 1 | 4 | 1 | 1 | 2 | 3 | 1 | 4 | 17 | |||||
| L. santarosai | Shermani str. LT 821 | pathogenic | 1 | 1 | 1 | 2 | 1 | 6 | 4 | 1 | 5 | 2 | 1 | 3 | 3 | 1 | 4 | 18 | |||||
| L. interrogans | Lai str. 56601 | pathogenic | 2 | 7 | 1 | 2 | 1 | 13 | 3 | 1 | 1 | 5 | 2 | 1 | 3 | 3 | 1 | 4 | 25 | ||||
| L. kirschneri | Grippotyphosa str. RM52 | pathogenic | 1 | 7 | 1 | 2 | 2 | 13 | 3 | 1 | 1 | 5 | 2 | 1 | 3 | 3 | 1 | 4 | 25 | ||||
| L. noguchii | Panama str. CZ214 | pathogenic | 1 | 7 | 1 | 2 | 2 | 13 | 3 | 1 | 1 | 5 | 2 | 1 | 3 | 3 | 1 | 4 | 25 | ||||
| L. weilii | Ranarum str. ICFT | pathogenic | 1 | 8 | 1 | 2 | 2 | 14 | 2 | 1 | 1 | 4 | 2 | 1 | 3 | 3 | 1 | 4 | 25 | ||||
| L. inadai | Lyme str. 10 | intermediate | 4 | 1 | 1 | 1 | 7 | 2 | 2 | 2 | 6 | 1 | 1 | 6 | 1 | 7 | 21 | ||||||
| L. fainei | Hurstbridge str. BUT 6 | intermediate | 5 | 1 | 1 | 1 | 8 | 2 | 2 | 2 | 6 | 1 | 1 | 4 | 1 | 1 | 6 | 21 | |||||
| L. licerasiae | Varillal str. VAR 010 | intermediate | 4 | 1 | 1 | 1 | 7 | 2 | 2 | 2 | 6 | 1 | 1 | 3 | 1 | 1 | 5 | 19 | |||||
| L. broomii | Hurstbridge str. 5399 | intermediate | 4 | 1 | 1 | 1 | 7 | 2 | 2 | 2 | 6 | 1 | 1 | 3 | 1 | 1 | 5 | 19 | |||||
| L. wolffii | Khorat str. Khorat-H2 | intermediate | 4 | 1 | 1 | 1 | 7 | 2 | 2 | 2 | 6 | 1 | 1 | 3 | 1 | 1 | 5 | 19 | |||||
| L. wolbachii | Codice str. CDC | saprophytic | 1 | 1 | 1 | 1 | 1 | 5 | 3 | 2 | 2 | 7 | 3 | 3 | 2 | 1 | 1 | 4 | 19 | ||||
| L. biflexa | Patoc str. ‘Patoc 1 | saprophytic | 1 | 1 | 1 | 2 | 1 | 6 | 3 | 2 | 6 | 1 | 3 | 1 | 4 | 3 | 1 | 4 | 20 | ||||
| L. meyeri | Hardjo str. Went 5 | saprophytic | 1 | 1 | 1 | 2 | 1 | 6 | 3 | 1 | 1 | 5 | 1 | 3 | 1 | 5 | 3 | 1 | 1 | 5 | 21 | ||
| L. yanagawae | Saopaulo str. Sao | saprophytic | 2 | 1 | 2 | 1 | 6 | 3 | 2 | 5 | 3 | 1 | 4 | 3 | 1 | 1 | 5 | 20 |