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. 2018 Apr 23;12:109. doi: 10.3389/fncel.2018.00109

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Copyright © 2018 Theis, Rózsa, Katona, Schmitz and Johenning.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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T- and R-type VGCCs do not contribute to synaptically evoked compound excitatory postsynaptic potentials (EPSPs) measured at the soma. (A1,B1) Extracellular synaptic paired-pulse stimulation evoked compound EPSPs under control conditions (black) and after wash-in of 3 μM TTA-P2 (green) and 300 nM SNX-482 (blue) 20–25 min after wash-in. (A2,A3,B2,B3) Time plots of normalized, binned (1 min) maximum amplitudes of EPSP1 (A2,B2) and EPSP2 (A3,B3) under control conditions (black) and during wash-in of TTA-P2 (green) and SNX-482 (blue). (A4,B4) Paired-pulse ratio (PPR) of the control conditions (black) and during wash-in of TTA-P2 (green) and SNX-482 (blue).