Table 5.
Changes in cytokine levels before and after the interventions in women with fibromyalgia.
| pg/mL | Exercise | Relaxation | ||
|---|---|---|---|---|
| n = 49 | n = 43 | |||
| Before | Δ | Before | Δ | |
| IFN-γ | 11.2 (9.0) | −1.8 (9.2) | 9.7 (12.3) | −0.4 (8.6) |
| IL-1β | 0.9 (1.9) | 0.0 (1.3) | 0.0 (1.6) | 0.6 (1.6) |
| IL-2 | 3.3 (4.9) | −0.3 (2.7) | 2.8 (3.1) | −0.3 (1.6) |
| IL-6 | 1.7 (2.5) | −0.2 (1.2) | 2.1 (2.4) | 0.2 (1.9) |
| IL-8 | 1.6 (1.9)# | −0.3 (1.6) | 0.8 (1.7) | 0.0 (1.3) |
| IL-10 | 8.0 (9.7) | −1.0 (6.3) | 7.9 (9.6) | 0.8 (7.4) |
| IL-17A | 10.8 (10.1) | −2.1 (7.6) | 9.2 (7.5) | −0.7 (5.9) |
| TNF-α | 4.5 (2.2) | −0.4 (1.8) | 4.0 (1.7) | −0.3 (2.0) |
| IL-1ra | 27.9 (67.8) | 22.1 (60.8) | 44.7 (105.4) | 21.4 (91.5) |
| IP-10 | 379.7 (230.4) | 2.3 (180.4) | 398.5 (219.7) | −33.5 (184.3) |
| MCP-1 | 318.0 (124.5) | 7.1 (131.5) | 289.6 (151.0) | 23.6 (76.3) |
| eotaxin | 107.0 (42.6) | −11.4 (53.0) | 106.9 (52.6) | −8.6 (34.6) |
Data show median (interquartile range) cytokine levels before and their change (Δ) after 15 weeks of progressive resistance exercise or relaxation therapy. Italic font indicates significant difference between groups (Mann–Whitney U-test; P = 0.037).