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. 2018 Apr 17;2018:7817360. doi: 10.1155/2018/7817360

Figure 4.

Figure 4

Spontaneous colonic cytokine production. (a) TNF is increased in DKO mice compared to IL10−/− and is restored to baseline in DKO mice that are reconstituted with BMMCs. (b) IL12p40 is increased in DKO mice compared to IL10−/− but is unaffected by BMMC reconstitution. (c) Colonic IL6 is similar between IL10−/−, DKO, and DKO mice reconstituted with BMMCs. (d) TNF is also restored to baseline in DKO mice reconstituted with IL10−/− BMMCs compared to DKO mice. IL10−/−: n = 25; DKO: n = 25; DKO-rMC: n = 13. ∗ p < 0.05, ∗∗ p < 0.01.