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. 2018 Apr 17;2018:7817360. doi: 10.1155/2018/7817360

Figure 5.

Figure 5

Mast cell deficiency in colitis results in dysregulation of many cytokines and chemokines. (a) Scatter plot representation of average fold change of 84 different cytokine and chemokine genes in IL10−/− compared to DKO mice from RNA extracted from whole colon. Dots above the lines are higher in DKO than in IL10−/− mice, and dots below the line are greater than 2-fold decreased in DKO compared to IL10−/− mice. (b) Reconstitution of DKO mice with BMMCs ameliorates the alteration of cytokines. Represents averaged fold change values in n = 5 mice per group.