Table 1.

Mast cell deficiency results in dysregulation of many different cytokines and chemokines. Fold change and p value of DKO and DKO-rMC mice compared to IL10^−/−. Significantly upregulated genes and downregulated genes indicated by bold and italic font, respectively (p = ≤0.1).

	Fold change and p value compared to IL10
	DKO		DKO-rMC
	Fold change	p value	Fold change	p value
Adipoq	0.93	0.605923	0.44	0.12537
Bmp2	0.36	0.00275	0.43	0.00352
Bmp4	0.47	0.003545	0.78	0.08664
Bmp6	0.38	0.027679	0.71	0.12534
Bmp7	0.55	0.0662	0.77	0.13341
Ccl1	2.3	0.06215	1.71	0.20753
Ccl11	0.54	0.157722	0.79	0.31294
Ccl12	0.46	0.020304	1.11	0.57195
Ccl17	1.12	0.862792	1.05	0.85839
Ccl19	1.4	0.281436	1.24	0.4384
Ccl2	1.46	0.268872	1.33	0.25702
Ccl20	0.84	0.90886	1.09	0.73897
Ccl22	1.23	0.36045	0.79	0.52381
Ccl24	0.86	0.287519	0.55	0.02211
Ccl3	2.5	0.304203	1.62	0.10923
Ccl4	3.6	0.132224	2.05	0.00244
Ccl5	5.19	0.059787	2.87	0.02972
Ccl7	1.27	0.259336	1.22	0.24594
Cd40lg	2.54	0.035975	2.89	0.01671
Cd70	0.94	0.73583	0.74	0.21501
Cntf	1.05	0.869816	0.79	0.11255
Csf1	0.54	0.011483	0.66	0.10244
Csf2	1.77	0.337615	1.28	0.73852
Csf3	1.93	0.18316	0.95	0.98266
Ctf1	0.49	0.131314	1.13	0.73413
Cx3cl1	0.57	0.024194	0.69	0.14404
Cxcl1	2.65	0.164314	1.48	0.2263
Cxcl10	1.69	0.232777	1.05	0.94321
Cxcl11	1.39	0.368579	0.96	0.96597
Cxcl12	0.44	0.009886	0.71	0.07872
Cxcl13	1.31	0.421716	1.09	0.73564
Cxcl16	1.02	0.830846	0.89	0.42328
Cxcl3	7.7	0.169696	0.95	0.91528
Cxcl5	3.37	0.212199	0.94	0.88692
Cxcl9	5.89	0.078554	3.3	0.06285
Fasl	3.09	0.119071	2.03	0.04219
Gpi1	1.07	0.640631	1.02	0.97433
Hc	0.75	0.681503	1.62	0.1135
Ifna2	0.93	0.605923	0.44	0.12537
Ifng	5.15	0.143744	2.21	0.13276
Il10	0.93	0.605923	0.44	0.12537
Il11	2.39	0.165436	1	0.82803
Il12a	0.54	0.098954	0.61	0.09123
Il12b	1.47	0.256595	1.62	0.12956
Il13	1.09	0.651106	1	0.99484
Il15	0.53	0.016916	0.73	0.07861
Il16	1.01	0.896996	0.56	0.04287
Il17a	1.12	0.484613	0.35	0.08594
Il17f	0.68	0.282624	0.55	0.00207
Il18	0.46	0.070874	0.87	0.26885
Il1a	3.9	0.220118	0.9	0.65997
Il1b	3.96	0.172113	1.26	0.38028
Il1rn	0.7	0.006867	0.73	0.03971
Il2	0.94	0.639082	0.48	0.13164
Il21	1.6	0.306708	0.44	0.12537
Il22	1.87	0.268256	0.54	0.12908
Il23a	0.8	0.611696	0.89	0.47794
Il24	1.45	0.684595	0.47	0.13168
Il27	1.45	0.322021	1.28	0.68824
Il3	1.06	0.871143	0.44	0.12537
Il4	1.67	0.323998	2.15	0.02924
Il5	0.73	0.547827	0.66	0.31967
Il6	3.97	0.227976	1.21	0.40714
Il7	0.48	0.180451	0.68	0.13566
Il9	0.93	0.605923	0.55	0.16928
Lif	1.11	0.576603	0.51	0.01984
Lta	0.65	0.44487	0.55	0.6218
Ltb	1.55	0.23314	0.83	0.91681
Mif	1.17	0.107953	1.18	0.29987
Mstn	1.13	0.736482	0.59	0.21285
Nodal	0.93	0.605923	0.52	0.15365
Osm	5.53	0.119627	1.56	0.12463
Pf4	0.47	0.030614	0.63	0.05057
Ppbp	1.14	0.986882	1.54	0.55059
Spp1	4.12	0.261256	1.77	0.93377
Tgfb2	0.51	0.048987	0.77	0.12043
Thpo	1.11	0.432272	1	0.80533
Tnf	2.54	0.151012	1.3	0.2214
Tnfrsf11b	0.91	0.948453	0.92	0.89644
Tnfsf10	1.16	0.779851	1.05	0.97127
Tnfsf11	2.2	0.211322	0.96	0.64542
Tnfsf13b	0.92	0.651414	0.93	0.44799
Vegfa	1.12	0.747986	0.92	0.55534
Xcl1	1.1	0.9224	1.28	0.48461