Table 2.
A. Allele distribution of TAP polymorphisms in women with and without high-grade cervical dysplasia | ||||||||
---|---|---|---|---|---|---|---|---|
| ||||||||
SNP | Allele | Control (n)* | Case (n)* | χ2 | P† | |||
TAP1 I333V | A | 261 | 119 | 5.40 | 0.02 | |||
G | 79 | 19 | ||||||
TAP1 D637D | A | 339 | 151 | 7.46 | 0.01 | |||
G | 95 | 21 | ||||||
TAP2 I1379V | G | 350 | 149 | 2.68 | 0.10 | |||
A | 70 | 19 | ||||||
TAP2 A665T | A | 335 | 133 | 0.27 | 0.60 | |||
G | 38 | 37 | ||||||
TAP2 Q687STOP | T | 285 | 120 | 0.18 | 0.67 | |||
C | 99 | 38 | ||||||
B. Allele distribution of TAP polymorphisms in high-risk HPV positive women with and without high-grade cervical dysplasia | ||||||||
| ||||||||
TAP1 I333V | A | 138 | 96 | 4.75 | 0.03 | |||
G | 50 | 18 | ||||||
TAP1 D637D | A | 185 | 126 | 8.99 | 0.00 | |||
G | 67 | 20 | ||||||
TAP2 I1379V | G | 209 | 125 | 0.22 | 0.64 | |||
A | 33 | 17 | ||||||
TAP2 A665T | A | 200 | 115 | 0.07 | 0.79 | |||
G | 54 | 29 | ||||||
TAP2 Q687STOP | T | 172 | 103 | 0.08 | 0.77 | |||
C | 48 | 31 |
Cases include women with CIN II and CIN III, controls include women with CIN I or no CIN.
P by Pearson's χ2 test.